Anatomy
Patient evaluation
Nonsurgical Management
Surgical Management
Miscellaneous
100
What muscle is attached to the base of each follicle?
Erector pili
100
What is the inheritance pattern of androgenic alopecia?
X linked dominant
100
Finasteride does not improve hair loss in what area?
Does not improve hair loss around temples
100
One follicular unit contains how many hairs?
2
100
What is the lethal dose of Botox in units?
2500u
200
Hair follicles spend most of their time in what phase?
Anagen
200
What is the classification scale used for male pattern baldness? How many types are there?
Norwood scale, 1-7 with two types of Type 3
200
Name three types of alopecia that are not amenable to surgical hair restoration.
-diffuse female pattern baldness
-nondonor dominant alopecia
-alopecia areata
-ACTIVE scarring alopecias
200
Micrografts and minigrafts contain how many hairs per grafts?
Micrografts: 1-2 hairs per graft
Minigrafts: 3-8 hairs per graft
200
How should patient wash their hair after hair transplantation?
For two weeks post op, patients should use "pour method", and mix light shampoo with warm water and pour over the scalp without massaging
300
What phase is characterized by keratinization of the hair base?
Catagen
300
What is the classification scale used for female pattern baldness? How many grades are there?
Ludwig scale, Grade 1-3
300
What is minoxodil's mechanism of action (broadly) and what does it do to the telogen and anagen phases?
Minoxodil is a vasodilator that shortens telogen phase, causing follicles to enter prematurely into the anagen phase. It also lengthens anagen phase.
300
When harvesting hair grafts by strip excision, the blade should be oriented in what direction and why?
Parallel to hair shafts to reduce follicular transection
300
Name two drugs or drug classes than potentiate the effects of Botox
-penicillinamine
-quinine
-CCBs
-aminoglycosides
400
Baldness and hair thinning develop when _____ phase shortens and _____ phase is prolonged
Baldness and hair thinning develop when anagen phase shortens and telogen phase is prolonged
400
"Androgenic alopecia follicles" have an increased amount of what enzyme? What does that enzyme do?
5a-reductase, converts testosterone to DHT
400
What is the pharmacological mechanism of action of finasteride and what is its effect on the hair follicle phases?
Finasteride is a 5a-reductase inhibitor that lowers follicle and serum DHT and promotes conversion of follicles to anagen phase
400
The anteriormost point of a newly designed hairline in a man undergoing surgical hair transplantation should lie where?
7.5 - 9 cm above glabella
400
What is the mechanism of Botox Type A?
Blocks the release of acetylcholine by inhibiting SNAP25 mechanism
500
Why are the temporal and occipital hair follicles good donor sites in surgical hair restoration procedures?
They are generally resistant to the effects of DHT
500
Name three types of alopecia that are amenable to surgical hair transplantation
-androgenic alopecia
-cicatricial alopecia
-traumatic alopecia
-traction alopecia
500
PRP can induce the proliferation of dermal papilla cells to promote hair growth by activating what growth factors? (full pts for naming two, +100 for each additional)
-FGF7
-beta catenin
-ERK
-Akt signaling pathway
500
How much of the scalp is available for hair transplantation in most male patients? (Can answer in percentage of follicular units)
12.5% of 12,500 hairs or 6250 FU
500
How does the optimal donor site in a man differ in patients less than 40 and greater than 40?
Less than 40: junction of middle and causal thirds of vertical distance between posterior fridge and lower hairline
Greater than 40: middle of vertical distance between posterior fridge and lower hairline