What are Hallucinogens?
LSD & Psilocybin
MDMA
Ketamine & Plant-Based Hallucinogens
Risks, Harms & Harm Reduction
100

What is the general term used in this lesson for drugs commonly known as psychedelics?

Hallucinogens.

100

What is the common street name for LSD?

Acid.

100

What are two common street names for MDMA?

Molly and Ecstasy.

100

What is the common nickname for ketamine?

Special K.

100

What is the safest way to completely avoid harm from drugs?

Not using them at all.

200

What are hallucinogens known to significantly alter in a person?

Mood, perception, thought processes, and self-awareness.

200

How is LSD most commonly taken?

Orally (liquid drops or blotter paper absorbed on the tongue).

200

Is MDMA classified as a stimulant, a hallucinogen, or both?

Both (stimulant and psychedelic).

200

What type of drug is ketamine medically classified as?

A dissociative anesthetic.

200

Why is mixing hallucinogens with substances like alcohol or cannabis risky?

It increases unpredictability and potential harm.

300

What two environmental or psychological factors influence how hallucinogens affect someone?

Set and setting (mindset and environment).

300

How long can an LSD trip last?

Up to 12 hours.

300

How long after taking MDMA do effects typically begin, and how long can they last?

Effects can begin around 45 minutes after use and last 4–6 hours.

300

Name one serious physical risk associated with ketamine misuse.

Kidney damage, slowed breathing, elevated blood pressure, or heart issues. Overuse of Ketamine can also cause bladder control issues. (peeing your pants)

300

What is a “sober sitter”?

A sober person who stays present to monitor and help someone using hallucinogens.

400

Why are hallucinogens difficult to classify?

Because their effects vary widely between individuals and can be unpredictable.

400

How long after ingestion do psilocybin mushrooms typically begin to take effect, and how long can they last?

Effects begin within about 20 minutes and can last up to 6 hours.

400

What dangerous overheating condition can MDMA cause?

Hyperthermia.

400

Which plant-based hallucinogen comes from the cactus species Lophophora williamsii?

Bonus 100 points: Where on the planet can this plant be found?

Peyote.

 Bonus: Southern United States and Mexico. Indigenous cultures have been using this drug for over 5000 years in cultural practices.

400

Why is drinking water especially important when using MDMA?

Because it can cause dehydration and overheating.

500

What does the term “contraindication” mean in relation to psychedelic treatment?

bonus 100 points: What psychedelic substance has been FDA approved to treat medication resistant depression?

A pre-existing condition that may disqualify someone from treatment due to potential risks. 

Bonus: Ketamine

500

What psychological symptoms can occur during a psilocybin experience that affect perception of reality?

Bonus 100 points: What mental health condition can hallucinogens mimic? 

Time distortion, difficulty distinguishing reality from fantasy, abnormal thoughts and speech, seeing moving objects.

Bonus: They mimic schizophrenia due to the excess of serotonin in the brain.

500

Why do people often experience a severe “comedown” after using MDMA?

Because it causes an overproduction of neurotransmitters like dopamine, leading to depletion afterward.

500

Which plant-based psychedelic is traditionally used in ceremonial contexts and is used by native peoples in the Amazon rainforest in South America?

Ayahuasca. Natural form of DMT

500

Why is it especially dangerous for someone with a history of anxiety, depression, or psychosis to use hallucinogens without medical supervision?


Because hallucinogens can intensify underlying mental health symptoms, potentially triggering panic, paranoia, or psychotic episodes, especially without professional support or a controlled setting.



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