Signs and symptoms
Can't control my arms, legs, torso!
what is chorea
How many repeats in mutant HTT?
what is >35 repeats
In Huntington's there is _____% of brain loss
what is 20-30%
This drug helps with chorea
what is Tetrabenazine
I am an autosomal dominant disease
what is Huntington's disease
This is especially hard to do when eating since I have Huntington's disease
what is Swallowing
One of the most common associated psychiatric disorders seen with Huntington's disease
what is major depressive disorder
One function of normal Huntingtin
what is: protein trafficking, vesicle transport, postsynaptic signaling, transcriptional regulation, and apoptosis.
Huntington's brain damage is typically located in?
What is the caudate nucleus and putamen
I assist with assist with speaking, communication tactics, and eating/swallowing
what is speech therapy
In North America Huntington's affects how many people?
what is 10 in 100 000
One cellular pathway mutant Huntingtin impairs
what is: transcriptional dysregulation, mitochondrial dysfunction, changes in axonal transport and synaptic dysfunction