Not the Myocardium🎒
Beyond the Stent 💈
Fatal Currents ☠️
Blocked! 🚨
Hot Mic 🤪
100
This hemodynamic sign of tamponade reflects exaggerated ventricular interdependence and is defined by a ≥10 mmHg inspiratory drop in systolic blood pressure.
pulsus paradoxus
100
This mechanism is most responsible for the no-reflow phenomenon post-PCI.
Microvascular obstruction from distal embolization
100
This ECG feature, not epsilon waves, is the most common abnormality in ARVC.
T-wave inversions in V1–V3
100
Prasugrel blocks:
P2Y12
100
“Follow up in sudden death clinic. Next available. Plenty of openings.”
Manish Assar
200
This pericardial disease entity is characterized by normal pericardial thickness, abnormal myocardial-pericardial coupling, and responds better to anti-inflammatory therapy than surgery.
transient constrictive pericarditis
200
This landmark trial demonstrated no mortality benefit of PCI over optimal medical therapy in stable CAD with moderate-to-severe ischemia.
ISCHEMIA
200
This ECG lead placement modification increases sensitivity for detecting Brugada patterns.
high right precordial lead placement (V1–V2 in the 2nd or 3rd intercostal space)
200
Ivabradine blocks:
Funny channels
200
“Oh you’re blind? Well, I look like Brad Pitt”
Alan Donsky
300
This ECG finding in acute pericarditis reflects atrial involvement and is most specific when present.
PR-segment depression
300
In STEMI patients with multivessel disease without shock, complete revascularization is recommended during this timeframe.
during index hospitalization or staged PCI
300
This pharmacologic agent is recommended for provocative testing to unmask Brugada syndrome in equivocal ECGs.
ajmaline (Procainamide or flecainide acceptable alternatives)
300
Bempedoic acid blocks:
ATP citrate lyase
(enzyme upstream of HMG-CoA reductase)
300
“I took her to the lab, because resuscitation was going really well…after over an hour.”
Subhash Banerjee
400
This cytokine is specifically targeted by anakinra and rilonacept in colchicine-resistant recurrent pericarditis.
Interleukin 1 (IL-1)
400
An IVUS MLA below this threshold in the left main generally warrants revascularization.
<6.0 mm²
400
This nuclear envelope protein mutation produces a cardiomyopathy marked by AV block, atrial fibrillation, and ventricular tachyarrhythmias years before LV dilation, distinguishing it from desmosomal disease.
LMNA
400
Zilebesiran blocks:
Angiotensinogen (siRNA therapy that blocks hepatic production of angiotensinogen)
400
“Did you find this strip in the trash?”
Jay Franklin
500
This X-linked lysosomal storage disorder can present with recurrent pericardial effusions and constrictive physiology, low-voltage ECG, and later restrictive cardiomyopathy, frequently leading to misdiagnosis as idiopathic pericardial disease.
Fabry Disease
500
In NSTEMI, early invasive strategy (<24 hours) is specifically recommended for patients with this GRACE score threshold.
GRACE score >140
500
This specific genotype of Long QT syndrome is most strongly associated with arrhythmic events triggered by exercise and swimming (MUST HAVE BOTH SYNDROME TYPE AND GENETIC MUTATION).
LQT1 (KCNQ1 mutation)
500
Vupanorsen blocks:
ANGPTL3 (regulator of triglyceride metabolism but had development halted due to hepatic toxicity)
500
“symptoms are chill….other than death”
Renato Quispe
