Which Forrester hemodynamic profiles is characterized by elevated filling pressures and low cardiac output?
Profile C
,
Which lipid-lowering drug inhibits PCSK9?
evolocumab or alirocumab
What is the definition of LV hypertrophy (include values for men and women)?
LV mass indexed: 95g/m2 women; 115g/m2 men
What class of antiarrhythmic is procainamide?
EMPEROR-Reduced and DAPA-HF tested which drug class?
SGLT2 inhibitors
“Cap / No Cap”
Cap = lie or exaggeration; No cap = no lie / for real.
“No cap, that tamponade was textbook.” = “Seriously, that was classic tamponade.”
Which temporary mechanical circulatory support device decreases LV preload and afterload?
Impella
For adults 40–75 years with diabetes and additional ASCVD risk factors, what LDL-C goal is recommended?
≥50% reduction in LDL-C and LDL <70 mg/dL.
What S' value supports normal RV systolic function per ASE right heart guidelines?
>= 9.5 cm/s
In AVNRT, which pathway conducts slowly and which conducts rapidly?
slow antegrade and fast retrograde
PARADIGM-HF compared sacubitril/valsartan to what?
enalapril
“Sigma”
Confident, lone-wolf energy — doing your own thing. EX: “She’s just quietly finishing all her notes — total Sigma energy.”
What is the SCAI shock stage for a patient requiring inotropes and/or vasopressors but with stable lactate?
SCAI Stage C
What is the mechanism of bempedoic acid?
inhibition of ATP citrate lyase
Bubbles appear in the LA 5 beats after opacification of the RA. What does this suggest?
Intrapulmonary shunt (not PFO/ASD).
What inherited sodium channelopathy causes coved ST elevation in V1–V3 and predisposes to polymorphic VT, often unmasked by fever or sodium-channel blockers?
Brugada Syndrome
What trial showed reduced mortality with ICDs in ischemic cardiomyopathy with EF <35%?
MADIT-II
“Drip”
Sharp, usually outfit or fashionable. Ex: “They've got procedural drip.” (= skilled swagger)
What pulmonary artery pulsatility index (PAPi) suggests RV failure?
PAPi < 1
PA pulse pressure / RA pressure
Which major trial supported the use of icosapent ethyl in patients with high triglycerides on statin therapy, and what is the triglycerides number indication?
REDUCE-IT; maximally tolerated statin and triglycerides >135
In the setting of chemotherapy cardiotoxicity monitoring, what drop in GLS is considered significant even if EF remains normal?
A relative reduction in GLS ≥15% from baseline.
What is the most common inherited arrhythmia syndrome?
Long QT syndrome
Which trial revived interest in early rhythm control for AF?
EAST-AFNET 4
“Gyatt”
Exclamation of surprise or admiration (like “whoa!”). EX: “Gyatt, that troponin is 8,000!”
This dimensionless index, calculated as (HR Ă— SBP) Ă· RAP, reflects overall cardiac workload and correlates with prognosis in advanced heart failure.
Cardiac Power Index
Which therapy under investigation targets lipoprotein(a) reduction through antisense oligonucleotide technology?
Pelacarsen
What are the 3 quantitative thresholds for severe tricuspid regurgitation on echo?
Vena contracta ≥0.7 cm
EROA ≥0.40 cm²
Regurgitant volume ≥45 mL
What syndrome occurs when a markedly prolonged PR interval causes atrial contraction during ventricular systole, mimicking pacemaker syndrome — despite no device being present?
"Pseudo-Pacemaker Syndrome", when the PR prolongation (usually PR >300ms), symptoms include dizziness, neck pulsations, and hypotension due to loss of AV synchrony

What initial trial showed that in stable CAD with moderate-to-severe ischemia, an initial invasive strategy did not reduce death or MI compared to optimal medical therapy (2020).
ISCHEMIA
“Skibidi”
Online nonsense trend term — used when someone gets embarrassed, owned, or roasted. “That intern just got skibidi’d on rounds.” (= roasted or called out)