Hematology
hematology
Oncology
Oncology
Oncology
100

Term for the stacking of red blood cells on a peripheral blood smear

Rouleaux (accept rouleaux formation)

100

 Elevation of this metabolic intermediate is associated with folate deficiency

 Homocysteine

100

Predominant histologic type of bladder cancer in the United States

Urothelial (accept transitional cell)

100

Most common malignancy associated with neurologic paraneoplastic syndromes

 Small cell lung cancer

100

Female cancer survivors are most likely to have had this type of cancer

Breast

200

The two hallmark findings of thrombotic thrombocytopenic purpura

Microangiopathic hemolytic anemia and thrombocytopenia

200

Eponym for calculation using CBC parameters useful in differentiating iron deficiency anemia from thalassemia

Mentzer index (accept erythrocyte count divided by the mean corpuscular volume)

200

Skin cancer type most prevalent following solid organ transplantation

Squamous cell carcinoma

200

 Eponymous syndrome for development of aggressive large-cell lymphoma in chronic lymphocytic leukemia or small lymphocytic lymphoma

Richter syndrome (accept Richter transformation)

200

Factor most predictive of survival in patients with early stage ovarian cancer

 Completeness of surgical debulking

300

Meaning of 'wet purpura'

Hemorrhagic blisters in mucous membranes, such as the oral mucosa

300

Coagulation study prolonged in hemophilia A and B

Activated partial thromboplastin time (accept aPTT or PTT)

300

 Hereditary hemochromatosis is most commonly associated with a mutation in this gene

HFE (accept C282Y)

300

Immunotherapy that uses T-cells manipulated to target specific tumor antigens

Chimeric antigen receptor T-cell therapy (accept CAR-T cell therapy or adoptive T-cell therapy)

300

Malignancy for which the Revised International Prognostic Index score is useful

Diffuse large B-cell lymphoma (accept aggressive non-Hodgkin lymphoma)

400

Most common drug associated with hemolytic anemia  

 Piperacillin

400

Clinical condition most commonly associated with 'bite cells' on a peripheral blood smear

Glucose-6-phosphate dehydrogenase deficiency (accept G6PD deficiency)

400

 Lung cancer that is immunoreactive for keratin and epithelial membrane antigen

Small cell lung cancer

400

 Acute leukemia displaying an ambiguous pattern of antigen expression making it unable to be assigned to one hematopoietic lineage

Mixed phenotype leukemia (accept hybrid leukemia; bilineage leukemia; biphenotypic acute leukemia)

400

Name of chemotherapy side-effect characterized by soreness, redness, and peeling of the skin of the palms and soles of the feet

 Hand-foot syndrome (also accept acral erythema, palmar-plantar erythrodysesthesia, hand-foot skin reaction, toxic erythema of the palms and soles, and Bergdorf's reaction)

500

Autoantibodies directed toward complexes of herparin and this protein result in heparin-induced thrombocytopenia

Platelet factor 4 (do not accept only platelet factor)

500

Scoring system to predict severity of ADAMTS deficiency in suspected thrombotic thrombcytopenic purpura

 PLASMIC Score

500

Acronym for the most common adjunctive therapy for stage III-IV colon cancer

 CAPOX (capecitabine and oxaliplatin) or FOLFOX (leucovorin, 5-fluorouracil and oxaliplatin

500

Medication with indications for treatment of acute promyelocytic leukemia and acne

Tretinoin (accept all-trans retinoic acid, ATRA)

500

 Optimal duration of trastuzumab therapy for HER2-positive breast cancer

 1 year

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