THROMBOCYTOPENIA
LYMPHOMAS
LEUKEMIA
POLYCYTHEMIA VERA
SICKLE CELL DISEASE
100

WHAT IS THE CAUSE OF THROMBOCYTOPENIA 

THE IMMUNE SYSTEM MISTAKENLY DESTROYS PLATELETS OFTEN DUE TO AUTOIMMUNE REACTIONS OR INFECTIONS LIKE VIRAL ILLNESS 

100

WHAT HAPPENS TO THE LYMPHOCYTES IN LYMPHOMA?

LYMPHOCYTES BECOME CANCEROUS AND PROLIFERATE UNCONTROLLABLY CAUSING LYMPH NODES AND OTHER LYMPHATIC TISSUES TO ENLARGE 

100

WHAT IS THE DEFECT IN LEUKEMIA THAT CAUSES UNCONTROLLED CELL GROWTH 

A MUTATION IN THE DNA OF HEMATOPOIETIC CELLS LEADS TO THE UNCONTROLLED PROLIFERATION OF ABNORMAL WBC

100

WHAT CAUSES THE INCREASED RED BLOOD CELL PRODUCTION IN POLYCYTHEMIA VERA 

A MUTATION IN THE JAK2 GENE LEADS TO THE OVERPRODUCTION OF RED BLOOD CELLS BY THE BONE MARROW 

100

WHAT CAUSES SICKLE SHAPED RBCS IN SICKLE CELL DISEASE 

A MUTATION IN THE HEMOGLOBIN GENE CAUSES HEMOGLOBIN S WHICH LEADS RBC TO TAKE ON A SICKLE SHAPE UNDER LOW OXYGEN CONDITIONS 

200

WHAT IS THE HALLMARK SYMPTOM OF THROMBOCYTOPENIA PURPURA?

EASY BRUISING AND PETECHIAE 

200

WHAT IS A COMMON SYMPTOM OF HODGKIN LYMPHOMA

PAINLESS SWOLLEN LYMPH NODES TYPICALLY IN THE NECK ARMPIT OR GROIN

200

WHAT SYMPTOMS ARE TYPICAL IN ACUTE LEUKEMIA 

SYMPTOMS INCLUDE FATIGUE PALLOR FREQUENT INFECTIONS EASY BRUISING AND BLEEDING DUE TO LOW PLATELET COUNT AND SWOLLEN LYMPH NODES 
200

WHAT SYMPTOM IS MOST COMMONLY ASSOCIATED WITH POLYCYTHEMIA VERA 

RED OR PURPLE SKIN, PARTICULARLY IN THE HANDS OR FACE DUE TO INCREASED BLOOD VOLUME AND VISCOSITY 

200

WHAT MAJOR SX IS ASSOCIATED WITH VASO-OCCLUSIVE CRISIS IN SICKLE CELL DISEASE 

SEVERE PAIN OFTEN IN BONES CHEST ABDOMEN OR JOINTS CAUSED BY THE BLOCKAGE OF BLOOD FLOW BY SICKLED RBCS 

300

WHAT LABORATORY FINDING IS TYPICALLY SEEN IN THROMBOCYTOPENIA 

A SIGNIFICANTLY LOW PLATELET COUNT OFTEN WITH NORMAL OR SLIGHTLY LOW WBC 

300

WHAT BLOOD TEST FINDING IS INDICATIVE OF LYMPHOMA 

ELEVATED WBC OFTEN ABNORMAL LYMPHOCYTES ALSO THE PRESENCES OF REED STERNBERG CELLS IN LYMPH NODE BIOPSY IS A DX FOR HODGKIN LYMPHOMA

300

WHAT LAB RESULT IS COMMONLY ELEVATED IN LEUKEMIA ESPECIALLY IN ACUTE CASES 

HIGH WBC OFTEN WITH LARGE NUMBER OF IMMATURE OR BLAST CELLS

300

WHAT BLOOD TEST FINDING HELPS DIAGNOSIS POLYCYTHEMIA VERA 

ELEVATED HEMOGLOBIN AND HEMATOCRIT LEVELS OFTEN WITH NORMAL OR SLIGHTLY ELEVATED WBC AND PLATELET COUNT 

300

WHAT LAB FINDING IS KEY DIAGNOSTIC INDICATOR OF SICKLE CELL DISEASE 

THE PRESENCE OF SICKLE SHAPED RED BLOOD CELLS AND A POSITIVE HEMOGLOBIN ELECTROPHORESIS TEST FOR HEMOGLOBIN S  

400

WHAT IS THE FIRST LINE TREATMENT FOR THROMBOCYTOPENIA 

CORTICOSTEROIDS TO REDUCE IMMUNE SYSTEM ACTIVITY AND INCREASE PLATELET PRODUCTION 

400

WHAT IS THE MOST COMMON TREATMENT FOR NON HODGKIN LYMPHOMA 

CHEMOTHERAPY OFTEN COMBINED WITH RADIATION THERAPY DEPENDING ON THE TYPE AND STAGE 

400

WHAT IS FIRST LINE TREATMENT FOR ACUTE LEUKEMIA 

CHEMOTHERAPY TO DESTROY LEUKEMIC CELLS AND ALLOW NORMAL BLOOD CELL PRODUCTION TO RESUME 

400

WHAT TREATMENT IS USED TO REDUCE THE RISK OF CLOTTING IN POLYCYTHEMIA VERA 

APHERESIS AND THERAPEUTIC PHLEBOTOMY AND INCREASE HYDRATION  

400

WHAT IS THE MAIN TREATMENT TO MANAGE SICKLE CELL DISEASE 

PAIN MANAGEMENT DURING CRISIS, HYDROXYUREA TO REDUCE SICKLING BLOOD TRANSFUSIONS AND BONE MARROW OR STEM CELL TRANSPLANTATION FOR SEVERE CRISIS 

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