Occurs early in fetal development and continues to mature throughout early childhood
Hematological system development
Two laboratory test to diagnosis anemia
direct Coombs test
hemoglobin electrophoresis
Ferritin
Serum iron
Lead levels
Responses manifested by chills, flushing, headache, chest pain, muscle pain, and elevated temperatures
Febrile responses
Deficiency in factor VIII
Hemophilia Type A
Condition of the neonate in which there is an increase breakdown of RBC that releases bilirubin.
Hyperbilirubinemia
Plasma portion of blood is composed of _____% solutes and ____% water.
10, 90
SCA crisis that can last up to 6 days and presents with severe joint, bone, and abdominal pain. May experience visual disturbances
Vaso-occlusive
Given to reduce urticaria responses
Diphenhydramine (Benadryl)
Christmas disease
Hemophilia Type B
Platelet count of less than 100,000/mL
Thrombocytopenia
Three functions of the blood
oxygenation
cellular nutrition
excretion of wastes
maintenance of acid base balance
regulation of body temperature
defense against foreign antigens
transport of hormones
Four clinical manifestations of anemia
Changes in behavior
Changes in skin
Heart & lung effects
GI upset symptoms
Urinary difficulties
Significant nervous system effects
Musculoskeletal symptoms
Hormones changes related to the endocrine system
Effects ENT (ear, nose and throat)
Occurs when the total volume of the transfused unit adds volume to the child’s vascular space.
Circulatory overload
Active bleeding, hematuria, impaired mobility, and reports of joint pain and stiffness
Assessment data
Bleeding into the tissues and petechiae on child’s skin
Idiopathic thrombocytopenia purpura
Where blood is formed
Hematopoietic system found within bone marrow and lymphatic system.
Condition with impaired production of hemoglobin, nutritional deficiency, or impaired or erythropoietin
Anemias
Given to improve the oxygen carrying capacity of blood
Packed red blood cells
PT, Factor specific assays, DNA testing
Laboratory tests
An inherited blood disorder that causes low hemoglobin, severe anemia, weakness, and fatigue, and pallor
Thalassemia major
The three main components of blood
Red blood cells
White blood cells
Thrombocytes
Most common form of anemia affecting children in the US
Iron-deficiency anemia
This document must be signed and on client's chart prior to procedure
Blood transfusion consent
Hemophilia is carried on this chromosome
X chromosome
Lipid soluble and accumulates in tissues
Indirect or unconjugated hyperbilirubinemia