Bleeding Disorders
Hemophilia B is a deficiency in?
Factor IX
When should you consider therapeutic anticoagulation in Factor V leiden patients?
All the indications for a normal patient lmao, unprovoked DVT/PE and Afib
What is the creatinine clearance threshold for use of lovenox?
<30mL/min
What is the cornerstone of DIC treatment?
Treat the underlying condition!
What's the name of the female lead vampire in Hotel Transylvania?
Mavis
DDAVP
Scoring system to determine pretest probability in HIT
4T score
Name the indications for reduced dose eliquis
Age greater or equal to 80
Weight is less than 60 kg
Creatinine is greater or equal to 1.5
What bacteria accounts for 90% of HUS cases in the US?
E. coli (O157:H7)
What disease likely contributed to the myth that vampire could not cross running water?
Rabies
What pathopneumonic sign is seen on peripheral blood smear with Bernard Soulier Syndrome
Large platelets
Three tests for antiphospholipid syndrome
Lupus anticoagulant, anticardiolipin antibodies, Anti-B2GP1
Name the two absolute indications for warfarin
Mechanical aortic and mitral valves as well as triple positive antiphospholipid syndrome
Aside from aortic stenosis, how else can someone acquire von Willebrand's Syndrome?
Hypothyroidism, myeloproliferative disorders, lymphoproliferative disorders, or dug induced from valproic acid and ciprofloxacin
What time-period did Edward the vampire get turned?
During the Plague of 1918
A PLASMIC score greater than or equal to X is indicative of TTP?
5
What is the platelet threshold to restart warfarin in a patient with HIT?
150k
What is the only FDA approved blood thinner for the treatment of thrombosis in patients with HIT?
Argatroban
What is the target hematocrit in polycythemia vera patients via phlebotomy?
<45%
What is the hopping vampire called from Chinese mythos?
Jiangshi
In HUS, what is the distinguishing lab and greater than what activity distinguishes this from TTP?
ADAMTS13 activity > 10%
What three vaccinations should be established in a patient before stating anti-C5 monoclonal treatment in paroxysmal nocturnal hemoglobinuria?
Meningococcal, pneumococcal, and Hemophilus.
What are the feared complication of warfarin use in pregnancy and when would you risk it? (not death)
Fetal Warfarin Syndrome, facial dysmorphism, skeletal abnormalities, and CNS abnormalities
You use it in if mom has a mechanical heart valve in second/third trimesters and possibly the first (lots of algorithm)
What medication is recommended for VTE prophylaxis in low risk multiple myeloma patients?
Aspirin 81-325 once daily while on myeloma therapy
Which vampire says "What is a man? A miserable little pile of secrets!"
Dracula from the Castlevania games