Etiology
Associated with bleeding, decreased uptake, and increased requirements (in pregnancy). The MOST common nutritional deficiency worldwide
What is Iron Deficiency Anemia
A patient with complaints of fatigue, tachycardia, brittle nails, koilonychia, and pica is suspicious for what type of anemia?
what is IDA
Peripheral smear of red blood cell shows basophilic stippling, and bone marrow has "ringed sideroblasts", this is d/t poisoning from what metal material?
what is lead poisoning
Treatment for Iron Deficiency Anemia
What is Ferrous Sulfate
increased absorption of ferrous sulfate occurs when taken with what?
What is ascorbic acid
the most common enzyme deficiency in humans, this is an X-linked disorder that is commonly associated with fava beans
what is Glucose-6-Phosphate Dehydrogenase Deficiency
what is the most common first presentation of sickle cell disease, what age is this seen?
What is Dactylitis, this is seen at 6-9 months
A patients labs show: MCV >100, decreased cobalamin, increased methylmalonic acid, increased homocysteine levels. what is the diagnosis?
what is Vitamin B12 deficiency
Gold standard for treatment of cobalamin deficency
IM vitamin B12 shot
Cobalamin deficiency is known as
what is vitamin B12 deficiency
X-linked recessive disease that lacks factor VIII
what is Hemophilia A
a patient complains of itchiness post warm shower, genetic studies reveal a JAK2 gene mutation. What is this suspicious for?
Polycythemia Vera
decreased factor IX and prolonged PTT is indicative of what inherited bleeding disorder?
Hemophilia B
Treatment for Hepatolenticular Degeneration
the primary cause of death in Paroxysmal Nocturnal Hemoglobinuria
what is thrombosis
The Philadelphia chromosome is a translocation between chromosomes 9 and 22, this is seen in what hematologic malignancy?
what is Chronic Myeloid Leukemia
A 62 year old patient presents with back pain, signs of nerve compression, and paraproteins on SPEP are significant for a monoclonal protein spike at the gamma region
what is multiple myeloma
Decreased vWF, prolonged PTT is suggestive of this most common inherited bleeding disorder
What drug is a vitamin k antagonist?
what is Warfarin
A dietary deficiency in this type of foods is commonly associated with Vitamin K deficiency
what are Green leafy vegetables
Acquired clonal disorders of the hematopoietic stem cells with a constellation of cytopenias, morphologic dysplasia, and genetic abnormalities
What are Myelodysplastic Syndromes
A patient presents with low platelet counts, anemia, fever, kidney disease, and neurologic findings. physical exam reveals petechia and purpura. What hematologic emergency is this worrisome for
What is TTP
Decreased platelets and fibrinogen, prolonged PT/INR and aPTT, elevated D-Dimer. What is the suspected disorder?
What is DIC
these medications should be absolutely avoided in patients with von Willebrand Disease
NSAIDs and Aspirin,
exception Celecoxib
This facilitates platelet adherence to subendothelial collagen
what is von Willebrand factor