RBCs
WBCs
Platelets
Coagulation
Transfusions
100

A client with sickle cell crisis reports chest pain and shortness of breath. O₂ sat is 92% on room air, and breath sounds are diminished at the bases. What is the nurse’s priority action?
A. Notify provider immediately
B. Administer oxygen
C. Obtain ABGs
D. Prepare for a chest x-ray

Administer oxygen

100

Which lab in leukemia requires immediate attention?
A. WBC 1,200 /µL
B. Platelets 60 K
C. Hgb 8 g/dL
D. Retic 0.5 %

WBC 1,200 /µL

100

Which symptom in ITP is life-threatening?
A. Nosebleed
B. New severe headache
C. Petechiae on arms
D. Gingival bleeding

New severe headache

100

Therapeutic aPTT on heparin?

A. 20–30 s 

B. 40–50 s 

C. 60–80 s 

D. >100 s

60–80 s

100

Transfusion reaction symptoms: chills, back pain, hypotension. First step?
A. Stop transfusion, keep line open with NS
B. Notify provider
C. Send urine to lab
D. Recheck blood ID

Stop transfusion, keep line open with NS

200

A client with iron deficiency anemia is prescribed ferrous sulfate. Which food should the nurse instruct the client to avoid within 1 hour of taking the medication?
A. Strawberries
B. Eggs
C. Spinach
D. Milk

milk

200

A client with multiple myeloma is most at risk for:
A. Bone fractures and hypercalcemia
B. Petechiae and epistaxis
C. Jaundice and pruritus
D. Pulmonary embolism

Bone fractures and hypercalcemia

Rationale: Bone destruction releases calcium → fractures + renal failure.

200

A client with TTP has urine output 8 mL/hr and confusion. Priority action?
A. Prepare for plasma exchange
B. Administer fluids
C. Give platelets
D. Monitor I&O

Prepare for plasma exchange

200

Therapeutic INR on warfarin?

A. 0.8–1.2 

B. 2.0–3.0 

C. 4.0–5.0 

D. >6.0

2.0-3.0

200

Crackles and dyspnea during transfusion indicate:
A. TACO
B. Sepsis
C. Hemolysis
D. Anaphylaxis

TACO (circulatory overload)

300

Which finding confirms vitamin B12 therapy is working for pernicious anemia?
A. Rising hemoglobin level
B. Pink, moist tongue and improved energy
C. Persistent paresthesia
D. Decreased reticulocytes

Pink, moist tongue and improved energy

300

Which finding is diagnostic of multiple myeloma?
A. Reed–Sternberg cells
B. Bence-Jones proteins in urine
C. Philadelphia chromosome
D. Auer rods

Bence-Jones proteins in urine

300

A client on heparin develops petechiae; platelets fall from 240 K → 85 K. What should the nurse do first?
A. Stop heparin immediately
B. Give protamine sulfate
C. Notify lab
D. Check aPTT

Stop heparin immediately

300

aPTT = 120 s while on heparin. Priority action?
A. Stop heparin and give protamine
B. Continue infusion
C. Reduce rate by 50 %
D. Document result

Stop heparin and give protamine

300

Post-transfusion labs show PT decreased and bleeding stopped. Which product was given?
A. FFP
B. PRBCs
C. Platelets
D. Cryoprecipitate

FFP

400

A client with aplastic anemia develops a temp of 100.9 °F. What’s the first action?
A. Give acetaminophen
B. Notify the provider
C. Obtain cultures
D. Start antibiotics

Notify the provider

400

A client receiving chemo for Hodgkin’s lymphoma suddenly develops facial swelling and dyspnea. What’s the cause?
A. Superior vena cava compression
B. Allergic reaction
C. Cardiac tamponade
D. Pleural effusion

Superior vena cava compression

Rationale: Mediastinal mass → venous obstruction → airway compromise.

400

A trauma client with DIC has oozing from IV sites. Which product should the nurse expect to administer?
A. FFP and cryoprecipitate
B. Platelets only
C. Vitamin K
D. Packed RBCs

FFP and cryoprecipitate

400

A client on tPA develops severe headache and unequal pupils. First action?
A. Stop infusion
B. Notify provider
C. Assess neuro status
D. Check BP

Stop infusion

400

Before starting a transfusion, the nurse must:
A. Verify patient + blood with another RN
B. Check vitals after 15 min only
C. Prime tubing with dextrose 5 %
D. Start within 1 hour of pickup

Verify with another RN

500

A client with polycythemia vera reports severe itching after showers. What should the nurse recommend?
A. Cool baths and antihistamines
B. Hot showers and lotion
C. Aspirin for itching
D. Warm compresses

Cool baths and antihistamines

Rationale: Heat worsens histamine release; cooling reduces pruritus.

500

A leukemia client post-chemo has uric acid 9.8 mg/dL, K⁺ 6.0 mEq/L, Ca²⁺ 6.5 mg/dL. What’s happening?
A. Tumor lysis syndrome
B. DIC
C. SIADH
D. Hyperparathyroidism

Tumor lysis syndrome
Rationale: Cell breakdown releases uric acid + K⁺ → renal failure risk.

500

Which medication is safest for anticoagulation in HIT?
A. Argatroban
B. Warfarin
C. Enoxaparin
D. Dabigatran

Argatroban

500

Massive transfusion causes tingling and muscle cramps. Likely cause?
A. Hypocalcemia from citrate binding
B. Hyperkalemia from cell lysis
C. Hypomagnesemia
D. Hypoglycemia

Hypocalcemia from citrate binding

500

Post-transfusion: fever 102 °F, tachycardia, hypotension, brown urine. Diagnosis?
A. Acute hemolytic reaction
B. Febrile non-hemolytic reaction
C. Allergic reaction
D. Bacterial contamination

Acute hemolytic reaction

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