Blood Cells
What is the lifespan of a mature RBC?
120 days
What blood type is referred to as the universal recipient?
Type AB (negative)
Type of foreign substance the body detects as “non-self” is known as?
Antigen
A blood clot that travels in the bloodstream to the lungs is called?
Pulmonary Embolism (PE)
The process of forming a blood clot is known as?
Coagulation; Hemostasis
Platelets are classified as what type of blood cell?
Thrombocyte
Which blood types are incompatible with type O (negative) blood?
A, B & AB
How many total clotting factors are there?
13
When an Rh- mother becomes pregnant with an Rh+ fetus, she receives RHOGAM to prevent what hemolytic disease of newborn (HDN)?
Erythroblastosis fetalis
What is the process of breaking down (dissolution) of blood clots?
Fibrinolysis
All blood cells differentiate from what type of stem cell?
Hemocytoblast
What type of antibodies are produced by an individual with type AB (negative) blood?
N/A
What substance is produced in response to the presence of antigens (elicits an IR)
Antibodies
A blood clot that forms in the lower leg is called?
Deep Vein Thrombosis (DVT)
Which enzyme converts fibrinogen to fibrin (clot)?
Thrombin
The process of forming blood cells is known as?
Hemopoiesis
What are the 2 indications for use of RHOGAM?
Blood Transfusions & SECOND exposure of Rh- mom to Rh+ fetus
What is the most abundant type of blood cell?
Erythrocytes (RBCs)
What is the MOA of RHOGAM?
Prevents the production of Rh+ antibodies (against fetus)
Following a vascular injury, what happens to the BVs in that area?
Vasoconstriction
Which organ produces erythropoietin (EPO)?
Kidneys (Renal Hormone)
What is the likelihood (%) an individual will be born with sickle cell anemia if both of their parents are carriers of the disease?
25%
What term describes the process of RBCs "clumping" together?
Aggregation
Which lab (other than RBCs) would indicate an individual is anemic?
Decreased Iron (Fe)
What are the 3 pathways in the fibrinolytic system?
Intrinsic, Extrinsic & Common Pathways