Tumors above the diaphragm
Tumors below the belt
2am Onco-Emergencies
Bone Marrow Blues
Packed Cell Problems
The Clot Thickens
Mystery Bag
100

This is used for the Treatment of breast cancer with HER2 overexpression (it also has the side effect of cardiomyopathy)

What is Trastuzumab? (also pertuzumab)

100

This is who should be offered genetic testing after being diagnosed with ovarian cancer

All women

100

This syndrome often presents with dyspnea, facial swelling, and a mediastinal mass

SVC syndrome

100

This is the initial treatment of chronic-phase CML

Tyrosine Kinase Inhibitors 

100

This condition's name is often a misnomer as it typically presents with pancytopenia and is characterized by severely decreased bone marrow cellularity. Sometimes caused by infections such as Parvovirus B19. 

Aplastic Anemia

100

Spurious cause of isolated thrombocytopenia

Bonus: How is this fixed?

Platelet clumping

Bonus: Have blood drawn into a tube containing citrate or heparin

100

This is the appropriate management after stopping warfarin in patients found to have an INR >10 without signs of bleeding. 

Oral Vitamin K

200

This is the most important factor when it comes to deciding prognosis of localized melanoma. 

Breslow Depth

200

This is the single most effective intervention for cervical cancer prevention

HPV vaccine

200

This is the first line treatment for patients with known brain metastases presenting with headache, depressed global consciousness, or features of herniation

Glucocorticoids

200

This test is the gold standard for diagnosing Myelodysplastic syndrome 

Bone Marrow Biopsy

200

This anemia is characterized by low MCV, normal hemoglobin electrophoresis, and normal iron.

α-thalassemia trait

200

This gene should be tested for in patients found to have abdominal thrombosis, splenomegaly, and/or portal hypertension.

Jak2

200

This chemotherapeutic agent is most commonly associated with causing an AKI

Cisplatin

300

This is the treatment of choice in patients with programmed death ligand 1-positive advanced H&N cancer

Pembrolizumab (Keytruda)

300

Patients presenting with a scrotal mass will most often have these tumor markers drawn. 

AFP and Beta HCG

300

These are two options for management of rapidly recurring pleural effusions

Indwelling pleural catheter or pleurodesis

300

This test is recommended when there is concern for lytic lesions from MM, but the whole-body, low dose CT scan was negative. 

Whole-body MRI

300

This therapy is indicated for ACS, Acute stroke, and acute retinal artery occlusion in patients with Sickle Cell Disease 

Exchange transfusion

300

These two tests are confirmatory for HIT if the ELISA for PF4 is positive. 

Serotonin release or heparin-induced platelet aggregation assay

300

This test will establish the diagnosis of Chronic Lymphocytic Leukemia

Peripheral blood flow cytometry

400

This is the most likely primary site of cancer in a woman presenting with an isolated axillary lymph-node adenocarcinoma. 

Breast

400

This infection is associated with gastric mucosa-associated lymphoid tissue lymphoma

Helicobacter pylori

400

These are used for Tumor lysis syndrome prophylaxis

Rasburicase and IV hydration

400

These are the diagnostic criteria of MGUS

1) M protein level <3g/dL

2) Clonal plasma cells <10% of bone marrow cellularity

3) No end-organ damage

400

This diagnosis is suggested by the development of fever and rash following PRBC tranfusion in immunocompromised patients, particularly those who have undergone stem cell transplantation. 

Tranfusion-associated GVHD

400

These three interventions are considered second-line treatments in ITP refractory to glucocorticoids or IVIG

Splenectomy, Rituximab, and Thrombopoietin receptor agonists

400

This deficiency can predispose patients to warfarin-related skin necrosis. 

Protein C deficiency

500

These scans are necessary for staging Small Cell Lung Cancer as asymptomatic metastases are not uncommon. 

CT C/A/P, Pet/Bone scan, and MRI brain

500

These drugs comprise the recommended treatment in all patients with Stage III colon cancer

Leucovorin, 5-FU, Oxaliplatin (FOLFOX) or Capecitabine and Oxaliplatin (CAPOX)

500

This is the treatment regimen indicated for patients with severe hypercalcemia of malignancy (Ca>14mg/dL) 

IV Hydration + IV bisphosphonate/Denosumab + Calcitonin

500

This Jak1/2 inhibitor is used both as symptom management in Primary myelofibrosis and in Polycythemia Vera patients who are intolerant to first line therapy. 

Ruxolitinib

500

This diagnosis is hallmarked by agglutinated erythrocytes and Direct antiglobulin test show C3 on erythrocyte surface

Cold agglutinin autoimmune hemolytic anemia

500

This intervention is paramount to the survival of patients presenting with MAHA, thrombocytopenia, and neurologic abnormalities. 

Therapeutic plasma exchange

500

This is the reversal agent for Dabigatran

Idarucizumab

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