This is used for the Treatment of breast cancer with HER2 overexpression (it also has the side effect of cardiomyopathy)
What is Trastuzumab? (also pertuzumab)
This is who should be offered genetic testing after being diagnosed with ovarian cancer
All women
This syndrome often presents with dyspnea, facial swelling, and a mediastinal mass
SVC syndrome
This is the initial treatment of chronic-phase CML
Tyrosine Kinase Inhibitors
This condition's name is often a misnomer as it typically presents with pancytopenia and is characterized by severely decreased bone marrow cellularity. Sometimes caused by infections such as Parvovirus B19.
Aplastic Anemia
Spurious cause of isolated thrombocytopenia
Bonus: How is this fixed?
Platelet clumping
Bonus: Have blood drawn into a tube containing citrate or heparin
This is the appropriate management after stopping warfarin in patients found to have an INR >10 without signs of bleeding.
Oral Vitamin K
This is the most important factor when it comes to deciding prognosis of localized melanoma.
Breslow Depth
This is the single most effective intervention for cervical cancer prevention
HPV vaccine
This is the first line treatment for patients with known brain metastases presenting with headache, depressed global consciousness, or features of herniation
Glucocorticoids
This test is the gold standard for diagnosing Myelodysplastic syndrome
Bone Marrow Biopsy
This anemia is characterized by low MCV, normal hemoglobin electrophoresis, and normal iron.
α-thalassemia trait
This gene should be tested for in patients found to have abdominal thrombosis, splenomegaly, and/or portal hypertension.
Jak2
This chemotherapeutic agent is most commonly associated with causing an AKI
Cisplatin
This is the treatment of choice in patients with programmed death ligand 1-positive advanced H&N cancer
Pembrolizumab (Keytruda)
Patients presenting with a scrotal mass will most often have these tumor markers drawn.
AFP and Beta HCG
These are two options for management of rapidly recurring pleural effusions
Indwelling pleural catheter or pleurodesis
This test is recommended when there is concern for lytic lesions from MM, but the whole-body, low dose CT scan was negative.
Whole-body MRI
This therapy is indicated for ACS, Acute stroke, and acute retinal artery occlusion in patients with Sickle Cell Disease
Exchange transfusion
These two tests are confirmatory for HIT if the ELISA for PF4 is positive.
Serotonin release or heparin-induced platelet aggregation assay
This test will establish the diagnosis of Chronic Lymphocytic Leukemia
Peripheral blood flow cytometry
This is the most likely primary site of cancer in a woman presenting with an isolated axillary lymph-node adenocarcinoma.
Breast
This infection is associated with gastric mucosa-associated lymphoid tissue lymphoma
Helicobacter pylori
These are used for Tumor lysis syndrome prophylaxis
Rasburicase and IV hydration
These are the diagnostic criteria of MGUS
1) M protein level <3g/dL
2) Clonal plasma cells <10% of bone marrow cellularity
3) No end-organ damage
This diagnosis is suggested by the development of fever and rash following PRBC tranfusion in immunocompromised patients, particularly those who have undergone stem cell transplantation.
Tranfusion-associated GVHD
These three interventions are considered second-line treatments in ITP refractory to glucocorticoids or IVIG
Splenectomy, Rituximab, and Thrombopoietin receptor agonists
This deficiency can predispose patients to warfarin-related skin necrosis.
Protein C deficiency
These scans are necessary for staging Small Cell Lung Cancer as asymptomatic metastases are not uncommon.
CT C/A/P, Pet/Bone scan, and MRI brain
These drugs comprise the recommended treatment in all patients with Stage III colon cancer
Leucovorin, 5-FU, Oxaliplatin (FOLFOX) or Capecitabine and Oxaliplatin (CAPOX)
This is the treatment regimen indicated for patients with severe hypercalcemia of malignancy (Ca>14mg/dL)
IV Hydration + IV bisphosphonate/Denosumab + Calcitonin
This Jak1/2 inhibitor is used both as symptom management in Primary myelofibrosis and in Polycythemia Vera patients who are intolerant to first line therapy.
Ruxolitinib
This diagnosis is hallmarked by agglutinated erythrocytes and Direct antiglobulin test show C3 on erythrocyte surface
Cold agglutinin autoimmune hemolytic anemia
This intervention is paramount to the survival of patients presenting with MAHA, thrombocytopenia, and neurologic abnormalities.
Therapeutic plasma exchange
This is the reversal agent for Dabigatran
Idarucizumab