Mystery/
Random
Random
What is the term for a decreased platelet count (platelet count <150)
Thrombocytopenia
Destruction of gut flora, dietary deficiency, and biliary duct obstruction are all potential causes of this condition.
Vitamin K Deficiency
The majority of coagulation factors are synthesized by this organ.
The Liver
These cells are incorporated into the clot during primary hemostasis and provide structural integrity.
Red Blood Cells
This test is useful in evaluation of the extrinsic pathway.
PT
This type of hemorrhage is associated with secondary hemostatic defects and typically presents as recurrent or excessive bleeding after minor trauma, dental extraction, or surgical procedure, or spontaneous internal bleeds into joints, body cavities, muscles and CNS.
Anatomic Hemorrhage
This condition can be triggered by a combination of injury-related acute inflammation, platelet activation, tissue factor release, hypothermia, acidosis, and hypoperfusion and leads to a reduction of ADAMST13.
Trauma Induced Coagulopathy
Factors XII, XI, IX, &VIII are all part of this coagulation pathway.
Intrinsic Pathway
One third of your platelet volume can be found in this organ.
The Spleen
A person with Hemophilia A is deficient in this coagulation factor.
Factor VIII
This is the primary substance responsible for initiating fibrinolysis.
TPA
This congenital anatomic bleeding disorder is most prevalent among those of Ashkenazi Jewish descent.
Hemophilia C
This factor is released by damaged endothelial cells and initiates one of the coagulation pathways.
(Tissue Factor/Factor III)
Platelet secretion occurs primarily during this phase of primary hemostasis.
Activation
Values for this test will be increased in all types of hemophilia.
PTT
This congenital bleeding disorder is also known as Christmas disease.
Hemophilia B
This condition is the most common acquired factor deficiency and primarily affects those over 60.
Autoanti-Factor VIII
This factor acts on fibrin to stabilize the final cross-linked clot.
Factor XIII
This platelet membrane receptor is vital in platelet adhesion.
Glycoprotein Ib
This factor will be the first to decrease in those suffering from liver disease.
Factor VII
A deficiency in these proteins is associated with increased risk of thrombosis.
Protein C & S
A patient’s labs come back as follows: Prolonged PT & PTT, decreased platelet count, decreased fibrinogen, & elevated D-dimer. ---What coagulopathy is the patient most likely experiencing?
DIC
These four coagulation factors are dependent on vitamin K for their synthesis.
Factors II, VII, and IX.
In this step of primary hemostasis platelets bind to each other by means of fibrin and GPIIb/IIIa.
Aggregation
This protein will be elevated in early liver disease, but decreased as the disease progresses in severity.
Fibrinogen