So Many Questions
If you are blind with no light perception, there are no such light cues. Your body clock is left to run its natural course making the timing of your circadian rhythms later and later, day after day until your circadian rhythms are essentially upside down from a typical 24-hour day.
How does Non-24 happen?
This clock controls the timing of the circadian rhythms from the release of hormones (chemicals that help the body function) to the sleep-wake cycle
What is a master body clock?
Non dash 24 dot com has very good information about Non-24-Hour Disorder and also provides links to a number of helpful articles.
I have more questions about Non-24. Where can I get answers?
You can sign up for Vanda’s mailing list and materials will be sent to you as they become available. You can sign up today for this list which may include email, direct mail, or phone communications
When the master body clock does not match the 24-hour day-night cycle, it may result in a Circadian Rhythm Disorder (CRD). Examples of CRDs include Shift Work Sleep Disorder, Delayed Sleep Phase Disorder, Jet Lag, and Non-24-Hour Disorder. On average, if sighted people were put in a cave, their master body clock would run longer than 24 hours.
What are circadian rhythm disorders?
Hunger at odd hours
Feeling energetic at night when most others are sleeping
Falling asleep or zoning out while interacting with others
Not feeling like yourself
Speech problems
Slowed reaction time
What is how does Non-24 Disorder affect people?
You may elect to avoid future communications from Vanda at any time by calling us directly at 1-855-856-2424 or sending an email to opt dash out at vandapharma dot com with your electronic mail address
What is can I opt-out at any time?
Though Non-24 is common in the blindness community, awareness is low. That’s why we’ve created fact sheets for you to print and give to family, friends, colleagues, and instructors, to help them understand Non-24 and the effect it can have on your life.
What is how do I talk about Non-24 with my friends and family?
Many people initially cope with Non-24 by forcing themselves to keep a typical schedule. This may result in a chronic sleep deficit, with symptoms that can mimic depression, attention deficit hyperactivity disorder, chronic fatigue syndrome, fibromyalgia, or just fatigue
Why is Non-24 often misdiagnosed?
You have trouble falling asleep or staying asleep.
You find yourself sleeping during the day or falling asleep unexpectedly.
You have sleep patterns that are continually different from most people you know.
The time your body wants to sleep seems to shift over time.
Your relationships may be affected.
You fight to stay awake during the day, at work or at school.
You’re frustrated because no one seems to understand what you’re going through.
You feel like you’re in a never-ending battle between sleeplessness and exhaustion
What is how do I know if I have Non-24?
There are many resources of information and services for the blindness community. These websites can link you to further advocacy and support organization
What other organizations/support groups or resources can you provide?
Since Non-24 is cyclical in nature, you should pay close attention to your sleep patterns, keep track of them, and share this information with your healthcare professional.
How do I know if I have Non-24?
There may be additional studies on Non-24-Hour Disorder. The best way to keep up to date on what is happening is to sign up to receive communications from Vanda Pharmaceuticals. If you choose to opt-in, we would notify you in the event that a new study is planned.
Will there be more studies on Non-24 Hour Disorder? If so how can I be notified about them?
You may have heard Non-24 referred to as many different names previously. You may have heard it referred to as Non-24-Hour sleep-wake disorder, free-running disorder, nonentrained disorder, or hypernychthemeral disorder.
If you would like to speak further with someone regarding treatment I can connect you with a specialist. You may call the support line toll-free between 9am and 8pm EST, Monday through Friday, at 1-844-438-5469 also visit www dot vandapharma dot com
What is, what can you tell me about treatments for Non-24/HETLIOZ® (tasimelteon)?
Non-24 is caused when the internal circadian clock in the brain and the sleep-wake cycle become different than or out of sync with the 24-hour light-dark cycle. In totally blind patients, their lack of light perception may lead to their internal circadian clock not being on the same schedule as the 24-hour day clock.
What is why do sighted persons develop Non-24?
There is an FDA-approved treatment for Non-24-Hour Sleep-Wake Disorder (Non24). Unfortunately, I am not in a position to provide more information about treatment as this is a support line for people living with Non-24 which provides information and education about Non-24.
What therapies are available for Non-24?
Non-24 may lead to long-term sleep deprivation. There are many long-term health effects of sleep deprivation
What is, what might the long-term health effects be?
Follow Non-24 on Twitter and/or Facebook to connect with others who may be experiencing symptoms of Non-24. The Twitter handle is @Non24HrDisorder. The Facebook page is fb.me/Non24HourDisorder.
How can I connect with others who may be experiencing symptoms of Non-24?
Yes, we are able to also record your telephone number and mailing address in order to keep you up to date with the latest information about Non-24-Hour Disorder.
What is I do not have access to a computer and I do not have an e-mail, can I still opt in?