General Herpes
Diagnosis and Screening
Antivirals
To cut, or not to cut?
Potpourri
100

This type of HSV is the primary etiologic agent of herpes labialis, gingivostomatitis, and keratoconjunctivitis.

What is HSV type 1?

100

The tests used to confirm the presence of HSV infection can be divided into two basic groups: viral detection techniques and this technique.

What is antibody detection techniques?

100

These are the three oral antiviral agents that are commonly used to treat HSV infections.

What are acyclovir, valacyclovir, and famciclovir?

100

Cesarean delivery is indicated in women with active genital lesions or prodromal symptoms, such as these, because these symptoms may indicate viral shedding.

What are vulvar pain or burning at delivery?

100

Transabdominal invasive procedures, such as chorionic villus sampling, amniocentesis, and percutaneous umbilical cord blood sampling, may be performed even when genital HSV lesions are present, but these procedures should be delayed until lesions appear to have resolved.

What are transcervical procedures?

200

This is the range that the the incubation period after acquisition of HSV-1 or HSV-2 is.

What is 2 days to 12 days?

200

Virologic tests are preferred for patients who present with these types of lesions and include viral culture and HSV antigen detection by polymerase chain reaction (PCR).

What are genital vesicles, ulcers, or other mucocutaneous lesions?

200

This is the dose of acyclovir and valacyclovir for a primary or first episode infection.

What are 400mg orally TID for 7-10 days, and 1g orally BID for 7-10 days?

200

In general, cesarean delivery is not recommended for women with a history of HSV infection and this during labor.

What are no active genital lesions or prodromal symptoms?

200

Unless there is a lesion on the breast, this is not contraindicated.

What is breastfeeding?

300

During the initial infection, the virus gains access to the sensory neurons, and then the infection becomes latent in this.

What is the sensory ganglia?

300

These are the types of patients where type-specific serologic assays that accurately distinguish between HSV-1 and HSV-2 antibodies may be helpful.

Who are patients who have a clinical history that suggests HSV but who do not present with active lesions or whose lesions have negative culture or PCR test results?

300

This is the dose of acyclovir and valacyclovir for a symptomatic recurrent episode.

What is 400mg orally TID for 5 days/800 mg orally BID for 5 days, and 500mg orally BID for 3 days/1g orally daily for 5 days?

300

For women with a primary or nonprimary first-episode genital HSV infection during the third trimester of pregnancy, cesarean delivery may be offered due to the possibility of this.

What is prolonged viral shedding?

300

This disease can be as lethal as that acquired during delivery.

What is postnatally acquired disease?

400

The is the incidence of new HSV-1 or HSV-2 infection during pregnancy.

What is 2%?

400

This test in asymptomatic pregnant patients with recurrent disease are not recommended.

What are routine antepartum genital HSV cultures?

400

This is the dose for acyclovir and valacyclovir for daily suppression. 

What is 400mg orally TID from 36 weeks until delivery and 500mg orally BID from 36 weeks until delivery.

400

Cesarean delivery is not recommended for women with these types of lesions, for example lesions on back, thigh, buttock.

What are nongenital lesions?

400

Although acyclovir was found in the breast milk in concentrations that were higher than the maternal serum, the amount of acyclovir in the breast milk was only this amount of that used for therapeutic doses in neonates

What is 2%?

500

These are the classifications that neonatal HSV infections can be grouped into.

What are disseminated disease (25%); central nervous system disease (30%); and disease limited to the skin, eyes, or mouth (45%).

500

This type of genital herpes infection during pregnancy constitutes a higher risk of perinatal transmission than does recurrent infection.

What is primary genital herpes infection?

500

In patients with active genital HSV lesions or prodromal symptoms and ruptured membranes at or near term, this should be performed as soon as the necessary personnel and equipment can be readied.

What is a cesarean delivery?

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