HIGH YIELD 1
HIGH YIELD 2
HIGH YIELD 3
HIGH YIELD 4
HIGH YIELD 5
100

A 22-year-old woman presents with a sudden onset of lower abdominal pain and missed period. On exam: hypotension, abdominal tenderness, and positive β-hCG. What is the most likely diagnosis?

Ruptured ectopic pregnancy

100

A 55-year-old man has epigastric pain that improves with eating. Likely diagnosis?

Duodenal ulcer

100

An 8-year-old has a sore throat, fever, and “sandpaper” rash. What’s the most likely diagnosis?

Scarlet fever

100

A 60-year-old diabetic has a foot ulcer with bone exposure. Next best step?

Order MRI of the foot

100

A 32-year-old woman presents with new-onset fatigue, pruritus after hot showers, and headache. CBC reveals elevated hemoglobin and hematocrit. Peripheral smear shows normal morphology. Erythropoietin level is low. What is the most likely diagnosis?

Polycythemia Vera

200

What medication is the best initial treatment for status epilepticus?

Lorazepam (Ativan)

200

What electrolyte abnormality is associated with flattened T waves and U waves on ECG?

Hypokalemia

200

What murmur is associated with a widened pulse pressure and bounding pulses?

Aortic regurgitation
200

A woman with bipolar disorder is found to have tremor, polyuria, and confusion. Which medication toxicity is suspected?

Lithium

200

A patient with a history of chronic liver disease presents with confusion, asterixis, and elevated ammonia levels. What is the most appropriate initial treatment?

Lactulose

300

A 65-year-old man with a history of smoking presents with painless hematuria. What is the most likely diagnosis?

Bladder cancer

300

 A systolic ejection murmur that radiates to the neck is most likely:

Aortic stenosis

300

Which condition is characterized by morning stiffness lasting more than one hour?

Rheumatoid arthritis

300

What is the diagnostic test of choice for pulmonary embolism in a stable patient?

CTA thorax

300

A 26-year-old woman presents with diplopia and ptosis that worsens throughout the day. She has difficulty chewing and weak extraocular muscles. Reflexes are normal. Which diagnostic test is most appropriate to confirm the suspected diagnosis?

Acetylcholine receptor antibody assay or edrophonium test

400

What is the most common cause of community-acquired pneumonia in adults?

Streptococcus pneumoniae
400

What is the most likely diagnosis in a young woman with fatigue, cold intolerance, and weight gain?

Hypothyroidism

400

A 4-year-old has barking cough and inspiratory stridor. Diagnosis?

Croup (laryngotracheobronchitis)

400

Microcytic, hypochromic red blood cells are found in which type of anemia? 

Iron deficiency anemia 

400

A 48-year-old man presents with progressive back pain, weight loss, and normocytic anemia. Labs show hypercalcemia and elevated total protein. Peripheral smear shows rouleaux formation. What is the next best step in diagnosis?

Serum protein electrophoresis (SPEP)

500

A patient presents with erythema migrans after a hiking trip. What’s the treatment?

Doxycycline

500

What is the first-line treatment for hypertrophic cardiomyopathy?

Beta blockers

500

What is the first-line antibiotic for uncomplicated cystitis in young women?

Nitrofurantoin

500

A patient has fever, sore throat, and posterior cervical lymphadenopathy. Monospot test is positive. What’s the causative agent?

Epstein-Barr virus

500

A 65-year-old man presents with painless jaundice, weight loss, and a palpable, non-tender gallbladder. What is the most likely diagnosis?

Pancreatic cancer 

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