Clinical Judgment
Opportunistic
Infections
ART Medication
Nursing Care
Transmission
100

A client with HIV and CD4 90 reports shortness of breath and O₂ saturation 86%. What is the first action?

Administer oxygen and assess respiratory status

100

Which infection most commonly occurs when CD4 < 200?
A. PCP pneumonia
B. Toxoplasmosis
C. Oral thrush
D. Cytomegalovirus

PCP is hallmark opportunistic infection below 200 CD4.

100

Goal of ART therapy?
A. Suppress viral load and restore immune function
B. Cure HIV infection
C. Decrease side effects only
D. Increase appetite and energy

 Suppress viral load and restore immune function

100

Client newly diagnosed with HIV says, “Everyone will hate me.” Nurse’s best response:
A. “It sounds like you’re worried about stigma.”
B. “Don’t think that way.”
C. “You shouldn’t care what others think.”
D. “Just keep it private.”

“It sounds like you’re worried about stigma.”

100

Three primary transmission routes:
A. Sexual, parenteral, perinatal
B. Airborne, fecal-oral, vector
C. Droplet, contact, ingestion
D. Sweat, saliva, urine

Sexual, parenteral, perinatal

200

The nurse receives four HIV patients. Who should be assessed first?

A. Fever 99.8°F, CD4 600
B. Productive cough and O₂ sat 88%
C. Mild nausea, CD4 480
D. Fatigue and headache

Productive cough and O₂ sat 88%

200

White plaques on tongue that scrape off easily indicate:
A. Oral thrush
B. Leukoplakia
C. Herpetic lesion
D. Aphthous ulcer

oral thrush


200

Client on protease inhibitor develops jaundice and ↑AST/ALT. What’s next?
A. Hold drug and notify provider
B. Continue medication with food
C. Give acetaminophen
D. Recheck labs in a month

Hold drug and notify provider

200

Client with HIV expresses hopelessness. Priority?
A. Assess for suicidal ideation
B. Offer diversional activities
C. Discuss ART side effects
D. Encourage group exercise

Assess for suicidal ideation

200

Effectiveness of PrEP when taken daily?
A. Up to 99% reduction in sexual transmission
B. 50% reduction
C. 25% reduction
D. None—it treats HIV

Up to 99% reduction in sexual transmission

300

A client with HIV has temp 103°F, confusion, and neck stiffness. Priority action?

Notify provider — possible meningitis; initiate neuro checks and infection precautions

300

HIV client has fever, headache, photophobia, and stiff neck. Likely infection?
A. Cryptococcal meningitis
B. CMV
C. Toxoplasmosis
D. Kaposi sarcoma

Cryptococcal meningitis

300

Missed ART doses lead to which complication?
A. Viral resistance
B. Liver failure
C. Bone marrow suppression
D. Electrolyte imbalance

Viral resistance

300

Client with oral thrush and weight loss. Nursing action?
A. Administer antifungals and soft high-protein meals
B. Restrict oral intake
C. Provide mouthwash with alcohol
D. Delay meals until thrush clears

Administer antifungals and soft high-protein meals

300

Nurse gets needlestick from HIV-positive patient. First step?
A. Wash site and start PEP within 72 hours
B. Document only
C. Wait for serology
D. Apply alcohol and continue working

Wash site and start PEP within 72 hours

400

A client with HIV develops petechiae, nosebleeds, and platelets 25,000. Priority intervention?

Institute bleeding precautions

400

Purple, non-painful lesions on skin/mucous membranes indicate:
A. Kaposi sarcoma
B. Petechiae
C. Psoriasis
D. Drug rash

Kaposi sarcoma

400

Why is ART given as combination therapy?
A. Prevent viral resistance and attack multiple replication stages
B. Decrease cost of treatment
C. Shorten therapy duration
D. Reduce side effects

Prevent viral resistance and attack multiple replication stages

400

Stage 3 client with chronic diarrhea. Priority intervention?
A. High-calorie, high-protein small meals and monitor fluids
B. Encourage fasting to rest bowels
C. Limit fluid intake
D. Provide low-protein diet

High-calorie, high-protein small meals and monitor fluids

400

Pregnant client with HIV asks about breastfeeding. Nurse response?
A. Avoid breastfeeding; HIV can pass through breast milk
B. Breastfeed only if viral load is low
C. Pump milk and boil before feeding
D. Breastfeeding prevents transmission

Avoid breastfeeding; HIV can pass through breast milk

500

A client with AIDS is unconscious and has a DNR order. Family demands resuscitation. What should the nurse do?

Honor the DNR and explain the legal obligation to follow patient wishes

500

A client with CD4 < 50 reports blurred vision and floaters. Which infection is suspected?
A. Cytomegalovirus retinitis
B. Toxoplasmosis
C. HSV keratitis
D. Candidemia

Cytomegalovirus retinitis

500

Client on ART reports numbness and burning in feet. Nursing action?
A. Assess pain, administer analgesic, report to provider
B. Stop ART immediately
C. Encourage walking
D. Apply ice packs

Assess pain, administer analgesic, report to provider

500

Client refuses ART. Best approach?
A. Explore beliefs and provide education
B. Force medication administration
C. Notify ethics immediately
D. Ignore refusal

Explore beliefs and provide education

500

Client with undetectable viral load asks if condoms are still needed. Nurse says:
A. Yes, they protect against other STIs and viral rebound risk
B. No, it’s completely safe
C. Only with new partners
D. Only during menstruation

 Yes, they protect against other STIs and viral rebound risk

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