Stages
Epidemiology
Structure
Life Cycle
Mystery
100
It takes ___ weeks (average) for antibodies against HIV to show up in blood tests.
What is 6 weeks?
100
The state with the highest rates of HIV diagnoses among adults and adolescents is ______.
What is Florida? Scary...
100
The family of viruses to which HIV belongs is ____.
What is Lentivirus?
100
Retroviruses replicate in this part of the cell.
What is the nucleus?
100
Herpes infection around the mouth is usually associated with HSV type _?
What is 1?
200
This stage of HIV appears within 3-6 weeks of infection.
What is Acute Retroviral Syndrome?
200
This racial/ethnic group has the highest number of people living with HIV in the US.
What is Black/African American?
200
This is the major capsid protein present in HIV, and is the target of anti-HIV antibodies.
What is p24?
200
gp120 on the HIV envelope must bind to the ___ receptor and either the ___ coreceptor or ___ coreceptor on the host cell.
What is CD4 and CCR5 or CXCR4?
200
This STI can lead to pelvic inflammatory disease (PID).
What is chlamydia?
300
CD4 counts at or below this level are required for an AIDS diagnosis.
What is 200 cells/mm3?
300
Approximately 1 in __ people are unaware of their HIV infection in the US.
What is 5?
300
These are the three viral enzymes present in the HIV viral core.
What are reverse transcriptase, protease and integrase?
300
These three genes code for the HIV viral proteins.
What are gag, pol and env?
300
Human herpes virus 8 causes this opportunistic infection.
What is Kaposi's Sarcoma?
400
This opportunistic infection is the only one that occurs when CD4 counts are less than 50 cells/mm3.
What is Mycobacterium Avium Complex (MAC)?
400
This percent of pregnant women infected with HIV will transmit the virus to their child if antiretrovirals are not used.
What is 25%?
400
The most genetic variation can be found in ______ ______ genes, which helps the virus evade the humoral immune response and makes vaccine development difficult.
What are envelope glycoproteins?
400
HIV inefficiently effects ______ T cells.
What are naive?
400
HIV infects these 3 types of cells.
What are T cells, macrophages and dendritic cells?
500
The HIV RNA "viral load" test detects HIV RNA within __ days of infection.
What is 9 days?
500
HIV-2 is primarily found in this part of the world.
What is Western, sub-Saharan Africa?
500
This transcription factor is triggered by a physiological immune response, but also induces HIV transcription.
What is NF-kB?
500
This enzyme transcribes integrated viral DNA (the provirus).
What is RNA polymerase II?
500
In the CNS, HIV can infect this type of cell.
What are microglia?
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