Infection
Rheumatologists should have low threshold for screening in this disease
What is HIV?
A bone condition that becomes more prevalent with HIV at CD4 60 or less and has risk factors like smoking, drinking, steroid use, increased lipids w/ protease inhibitors
What is osteonecrosis/avascular necrosis?
This is a typically self-limiting seronegative, oligoarticular arthropathy, esp knees, ankles
What is HIV associated arthritis?
This centralized pain disorder can feel like myalgias but has no objective clinical findings except for many tender points and occurs in 10-30% of HIV pts
What is fibromyalgia?
A flare of this relatively common skin condition is seen in late stage HIV and is mediated by CD8 T cells
What is psoriasis?
This cell gets depleted in HIV
What is CD4+ T cell ct?
ART can lead to this bone condition
osteoporosis
This condition is seen in a patient who has pre-existing SLE or RA and gets worse despite having increasing CD4+ T cells with decreasing viral load on ART
What is IRIS?
HIV muscle condition that is characterized by ragged red fibers
What is AZT/ Zidovudine toxic MITOCHONDRIAL myopathy?
Mimicker for Sjogren's
What is DILS
This infection is characterized by flower cells on histology
What is HTLV1?
This infection can cause hypertrophic osteoarthropathy
What is PJP?
These are the 2 most common manifestations of reactive arthritis in HIV
What are Seronegative oligoarthritis of LE, urethritis?
These 2 medications can cause increased chance for rhabdomyolysis
protease inhibitor, statin
Mimicker for SLE
What is HIV associated immune complex kidney (HIVIC) dz?
This bug is a common culprit in IVDU and pyomyositis
What is Staph aureus?
Salmonella osteomyelitis and septic arthritis is rare but more common in this sub-population of HIV pts
What is hemophilia?
This is an acute HIV-specific condition with arthralgias in knees, shoulders, elbows that is self-limiting
What is Painful articular syndrome?
You should screen for this concomitant infection in HIV-associated polymyositis
What is toxoplasmosis gondii? (can cause a myopathy itself)
Muscle biopsy can differentiate this condition from others in HIV due to the non-inflammatory histology
What is HIV muscle wasting disease/ slim disease?
atypical mycobacterium and fungal MSK infections become more frequent at this CD4 count
What is CD4 T cell 100?
This is a key feature on radiography of hypertrophic osteoarthropathy
What is periosteal reaction in long/tubular bones?
Immunosuppression in HIV/AIDS should be used with caution because it can cause this HIV/AIDS-associated malignancy
What is Kaposi sarcoma (HHV8)?
fever, redness, swelling, localized muscle pain is seen in this condition and most commonly occurs in this particular muscle
What is pyomyositis in the quadriceps?
Pyomyositis becomes more common at this CD4 count
What is 200?