HIV
When should a person with HIV infection initiate treatment?
As soon as possible.
First line treatment for candidemia
Micafungin
Define fever?
Temperature greater than 100.9 degrees F
38.3 Celsius for the internationals
In patients who have been diagnosed with TB what other disease should be screened?
HIV
In the TV show "The Last of Us" this fungus evolved to infect humans due to global warming.
Cordyceps
Name 3 symptoms of an acute HIV infection.
Fever, fatigue, myalgia, rash, headache, pharyngitis, lymphadenopathy, arthralgia, night sweats, diarrhea
What is the morphology of blastomyces?
Dimorphic round budding yeast
What are the categories of fever of unknown origin?
Classic, health care–associated, neutropenic, and HIV-associated
For an organ transplant patient, what size of a PPD induration indicates tuberculin positivity?
Greater than or equal to 5mm
What is this Michael Crichton book about an extraterrestrial microbe?
The Andromeda Strain
At what number of copies/mL of HIV RNA level is a person considered "undetectable."
200
With regards to coccidiomycosis, which populations are at highest risk for disseminated infections?
Children younger than 5 years, pregnant patients, and those older than 50 years old
Temperature once > 101F (38.3C) or sustained temperature over 1 hour >100.4F (38.0C)
+ absolute neutrophil count of <500 cells/uL
Before initiating these immunosuppressive medications, all patients should be screened for active or latent tuberculosis.
What are tumor necrosis factor α inhibitors?
In what mobile game do you design a pathogen to attempt to wipe out humanity? (And why is greenland so hard to infect?)
Plague Inc.
What are at least3 specific vaccines that all adult HIV patients should receive?
Pneumococcal, Hepatitis B, quadrivalent meningococcal, zoster
With regards to cryptococcal meningitis, what is the most effective way of reducing ICP?
Serial/Sequential Lumbar Punctures
Safety pin staining/bipolar staining is used to demonstrate the morphology of which bioterrorism infectious agent?
Yersinia pestis
Tuberculosis in patients with HIV infection may be complicated by this syndrome, which can be prevented by delaying antiretroviral therapy initiation
What is immune reconstitution inflammatory syndrome? (IRIS)
What real pathogen is the basis of vampire folklore?
Rabies
What two diseases do you administer prophylactic antibiotics in HIV patients?
Pneumocystis jirovecii Pneumonia
Toxoplasma gondii
Galactomannan Antigen
Everyone goes to Dr. Alden's house and is diagnosed with a mild course of a mysterious disease ("Aldenitis" if you will), after petting his pet rabbit. What antibiotics should be started?
Doxycycline or ciprofloxacin for 14 days
What are all 3 options for latent TB infection treatment?
Isoniazid plus rifapentine once weekly for 3 months
Rifampin daily for 4 months
Isoniazid plus rifampin daily for 3 months
What is the corporation in Resident Evil that develops multiple viruses/parasites/bioweapons?
Umbrella Corp