Diabetes
Homeostasis
Glucose Regulation: On a cellular level
Glucose Homeostasis
Negative Feedback
100

The main characteristic of diabetes

High blood glucose

100

Homeostasis

What is the maintenance of a constant internal condition

100

What is the name of the protein that insulin binds to

insulin receptor

100

Molecule that is source of energy for cells in our bodies.  It is also our blood sugar.

glucose

100

How does the body respond to cold temperature?

-shivering

-increased metabolic activity

-vasoconstriction of blood vessels near the skin

200

The hormone produced by beta cells in the pancreas

Insulin

200

When the body reacts to bring the body back into balance 

What is a negative feedback loop

200

What is the name of the protein that is signaled in the cell after insulin binds to the receptor

The Glut 4 protein or glucose 4 transporter protein.

200

Insulin and glucagon are produced by which organ?

Pancreas

200

How does the body respond to warm temperature?

-sweating

-lowered metabolic activity

-vasodilation of blood vessels near skin

300

When target cells in the liver and muscle cells are resistant and desensitized to the insulin that the body produces

Type 2 diabetes

300

Glucose is stored as what in liver and muscle cells?

glycogen

300

Which protein does glucose use to enter cells?

GLUT 4 transport protein

300

hormone that lowers blood glucose levels.

What is Insulin?

300

What effect will glucagon have on the body?

The liver and muscle cells will convert glycogen into glucose and blood sugar will increase.

400

Cause of Type 1 diabetes

Inability to produce insulin/autoimmune disease attacking beta cells in the pancreas

400

One example of a negative feedback loop to maintain homeostasis

What is body temperature regulation/glucose regulation/blood pressure regulation 

400

What must occur for glucose to enter cells in the muscle and liver tissue?

Insulin must bind to receptors on the membrane so glut 4 transport proteins merge with the cell membrane and glucose can enter the cell.

400

Hormone that increases glycogen being broken down into glucose

What is Glucagon?

400

What effect will insulin have on the body.

Insulin allows glucose to be taken into cells.  This decreases blood glucose as glucose can then be converted into glycogen for storage.

500

Insulin injections are a common treatment for this type of diabetes.

What is Type 1 diabetes

500
The root words of equilibrium mean what?

equa:

libra:

equa:  equal

libra:  balance

500

What happens after insulin binds to insulin receptors in the cell membrane of liver and muscle cells?

Signal transduction cascade occurs stimulating the GLUT 4 protein to merge with the cell membrane.

500

The name of the cells in the pancreas that produce the hormone glucagon.

What are Alpha cells?

500

What is the next step in the negative feedback mechanism:

1.  Conditions move from a set-point.

2.  Corrective mechanisms are activated.

3.  Conditions return to the set point.

4.?

The corrective mechanism must be switched off.

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