The capacity of a single genotype to exhibit variable phenotypes in different environments.
What is phenotypic plasticity?
100
5' to 3'
In which direction does DNA synthesis proceed?
100
Promoter region.
What do we call the regions that occur fixed distances upstream from the beginning of the transcriptional unit to which transcription factors bind?
100
They enhance the expression of tandem arrays of linked genes.
What is a LCR or Locus Control Region?
100
The collection, classification, storage and analysis of genomic information.
What is bioinformatics?
200
Human skin color variation.
What is the example of a multifactorial and polygenic trait from class that has been shaped by positive selection, genetic drift and purifying selection?
200
DNA polymerase II
What is name of the enzyme used to synthesize DNA using a DNA template?
200
Alternative RNA splicing.
What process gives rise to several different mRNA molecules all derived from the same RNA transcript?
200
The mechanism by which changes in the pattern of inherited gene expression occur in the absence of alterations or changes in the nucleotide composition of a given gene
What is epigenetics?
200
Continuous portions of DNA, 1–400 kb in length, that map to two or more genomic locations, which typically share >90% sequence homology.
What are segmental duplications?
300
The attribute of a polygenic trait in a population that expresses how much of the total phenotypic variation is due to genetic variation
What is heritability?
300
During DNA replication, when one purine is improperly placed instead of the other purine.
What is a transition mutation?
300
Polyribosome.
What do we call an mRNA attached to several ribosomes at one time?
300
Sites of methylation and gene silencing upstream from pol II genes.
What is a CpG island?
300
The portion of the genome represented in mature mRNA (approximately 1 - 1.5% of the HG).
What is the exome?
400
A probability of 1/2. (This is a relatedness question).
What is probability that a given allele will be shared between sibilings, or between parent and child?
400
Frameshift.
What term describes the result of an indel mutation?
400
Dentinogenesis imperfecta.
What is the name of the disorder given in class as an example of improper post-translational modification?
400
miRNA (MicroRNA)
What type of RNA binds to mRNA, rendering it unable to be translated?
400
Sequences in the genome that have close similarities to one or more paralogous functional genes, but in general are unable to be transcribed
What is a pseudogene?
500
Provides a statistical correlation between a SNP or other marker and a phenotype, using DNA sequence data obtained for populations.
What is a Genome-Wide Association.
500
A nonsense mutation.
What do we call the type of single nucleotide substitution mutation that causes the premature termination of protein synthesis?
500
The proteasome.
What is the name of the protein complex that destroys proteins tagged by ubiquitin?
500
Polypeptide shortening and division into smaller chains; the addition of carbohydrate to a polypeptide.
What are different types of post-translational modification?
500
ALU - a type of nonLTR transposon in the SINE family.
What is the most abundant sequence in the human genome?