Diagnoses
Things a neurologist may assess when diagnosing a patient that potentially has HD. (3 answers!)
What are reflexes, balance, movement?
The average number of CAG repeats until growth becomes rapid
What is 80 CAGs?
Age range when symptoms start to appear
What is 30-50 years?
Number of years it takes for a drug to become FDA approved
Gene affected by Huntington's
Most effective and accurate method for testing for HD
What is a direct genetic test?
Number of brains studied in the Harvard Medical School study (total)
What is 103 brains?
Name of the most common symptom of HD (starts with a C!!)
What is chorea?
What are beta blockers?
DNA sequence repeated because of Huntington's
What is the CAG sequence?
An example of something you may see on a CT/MRI scan that may indicate the patient has HD (2 answers!)
What is brain atrophy or enlargement of ventricles?
The droplet single-cell RNA-sequencing can do this. (2 answers!)
What is analyzing gene expression and the length of a CAG repeat?
Part of the brain that HD attacks
Popular delivery method being explored for new drugs targeting huntingtin protein levels in blood
What are oral drugs?
Probability (percent) of a child carrying the mutation if one parent is affected
What is 50%?
What MRI stands for
What is magnetic resonance imaging?
What the Harvard Medical School research group found 150+ CAG repeats would do to neuronal health
What is distorted gene expression?
Cure to Huntington's
What is does not exist?
Most promising and recent drug (bonus points if you say the % reduction of disease progression)
What is AMT-130?
When individuals with no family history of HD have the disease
What is sporadic HD?