To screen or not to screen
Statin O' Statin
Primary Prevention
My achey breaky heart (and muscles)
New kids on the block
100

This age is when we begin screening for high cholesterol in adults

What is age 21?

100

Patients with diabetes mellitus should be on this regardless of their LDL

What is a moderate intensity statin?

100

These diets have been associated with lower all-cause mortality than standard/control diets.

What is plant-based and mediterranean diet?

100

For patients with established ASCVD, this is the goal LDL level

What is < 70 mg/dl?

100

The addition of non-statin therapies for patients with known ASCVD should be considered at this LDL threshold.

What is > 70 mg/dl?

200
In an average risk adult, this is how often we screen for hyperlipidemia

What is q5 years?

200

Atorvastatin 40mg and rosuvastatin 20 mg are both this class of medication

What is a high intensity statin?
200

Adults should engage in this amount of exercise per week to reduce their ASCVD risk.

What is at least 150 minutes of accumulated moderate intensity or 75 minutes of vigorous intensity exercise?

200

Consider checking lipid panel at this interval after starting a statin in order to titrate the dose.

What is 4 to 12 weeks after initiation? 

200

For patients with persistent fasting hypertriglyeceridiema > 500, consider adding these medications to their statin therapy. 

What is fenofibrate or icosapent ethyl? 

300

This calculator helps clinicians decide if a patient would benefit from statin therapy

What is the ASCVD risk calculator?

300

Recommendation for high intensity statin should be made with this LDL

What is greater than or equal to 190 mg/dl?

300

An LDL goal of less than this is considered ideal for patients without known ASCVD. 

What is < 100 mg/dl?

300

For patients with statin associated side effects, consider these two different treatment options. 

What is lower statin dose or change statin?

300

This medication is recommended as the initial nonstatin therapy in patients with clinical ASCVD who are receiving maximally tolerated statin therapy and have an LDL-C level > 70 mg/dL

What is ezetimibe? 

400

A coronary artery calcium score should NOT be used for screening purposes in these groups of people. 

What are LOW risk and HIGH risk individuals based on ASCVD calculator?

400

A high-intensity statin lowers LDL by this much on average

What is > 50 %?

400

Generally, we might consider starting statins at this age for primary prevention of ASCVD

What is age > 40?

400

This medication that reduces triglycerides should be avoided with statins due to increased risk of statin associated muscle side effects.

What is gemfibrozil?

400

For very-high risk patients with clinical ASCVD, this is the next medication to be considered after max dose statin + ezetimibe.

What is a PCSK9 mAB? 

500

For our pediatric patients, we might consider screening at this age

What is between 9-11, and again between 17-21?

500
For patients with borderline (5-7.5%) or intermediate risk (7.5-20%) of ASCVD, this additional test might offer some additional information to aid in decision making around statin therapy

What is a coronary artery calcium score?

500

Under the age of 40, we might consider a statin for this hereditary diagnosis

What is familial hypercholesterolemia?

500

This is a very rare condition that would prompt discontinuation of statin

What is statin induced rhabdomyolysis?

500

This medication is the newest kid on the block and can be considered if additional LDL lowering is needed after statin + ezetimibe + PCSK9 mAB.

What is bempedoic acid?

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