Thyroid physiology
Causes and risk factors
Signs, symptoms and diagnosis
100

What are the 2 main hormones produced by the thyroid gland?

a) Insulin 

b) T3 / T4

c) ACTH

B) T3 / T4

100

What is the most common cause of hypothyroidism?
A) Graves’ disease
B) Hashimoto’s thyroiditis
C) Diabetes mellitus


B) Hashimoto’s thyroiditis

100

Which symptom is common in hypothyroidism?
A) Fatigue
B) Hyperactivity
C) Excess sweating


A) Fatigue

200

Which hormone stimulates the thyroid gland?

A) TSH
B) T4
C) TRH


A) TSH

200

A lack of which mineral can cause hypothyroidism?
A) Iron
B) Calcium
C) Iodine


C) Iodine

200

People with hypothyroidism often experience:
A) Heat intolerance
B) Cold intolerance
C) Increased appetite without weight gain


B) Cold intolerance

300

Which gland releases TSH?
A) Thyroid gland
B) Hypothalamus
C) Pituitary gland


C) Pituitary gland

300

Which medication may contribute to hypothyroidism?
A) Amiodarone
B) Paracetamol
C) Ibuprofen


A) Amiodarone

300

What is the main screening test for hypothyroidism?
A) TSH
B) Glucose
C) Hemoglobin


A) TSH

400

Which structure releases TRH?
A) Hypothalamus
B) Thyroid gland
C) Adrenal gland


A) Hypothalamus

400

Who has a higher risk of developing hypothyroidism?
A) Men
B) Women
C) Children only


B) Women

400

Which test confirms the degree of thyroid hormone deficiency?
A) Troponin
B) Free T4
C) Creatinine


B) Free T4

500

What is the correct sequence of hormone regulation?
A) Thyroid → Hypothalamus → Pituitary
B) Hypothalamus → Pituitary → Thyroid
C) Pituitary → Thyroid → Hypothalamus


B) Hypothalamus → Pituitary → Thyroid

500

Which of the following is NOT a risk factor for hypothyroidism?
A) Family history
B) Autoimmune disease
C) Regular exercise


C) Regular exercise

500

Which laboratory finding suggests primary hypothyroidism?
A) Low TSH and high T4
B) High TSH and low Free T4
C) High TSH and high T4


B) High TSH and low Free T4

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