All About
That Base
That Base
The amount of base needed to increase the pH to 7.40
What is base deficit
Temporary organ used by the fetus for gas exchange
What is the Placenta?
Increased accumulation of hydrogen ions in the blood
What is Acidosis?
Major generator of ATP for all mammals
What is the Kreb Cycle?
Carries blood from the placenta to the fetus
What is Umbilical Vein?
Supportive value used to determine the degree of metabolic influence on the pH for an arterial blood gas in a newborn during the intrapartum period
What is High Base Deficit?
Innate method of metabolic conservation triggered by hypoxia resulting in bradycardia and shunting of blood to vital organs
What is Diving Reflex?
Key finding is abnormal carbon dioxide (pCO2) along with abnormal pH when diagnose the primary driver of acid/base imbalance
What is Respiratory?
Respiration type utilizing oxygen and glucose.
What is Aerobic?
Decreases with increasing oxygen saturations and fluid dissipation shortly after birth
What is Pulmonary Vascular Resistance?
Acid likely responsible for significantly increased base deficit
What is Lactic Acid
Infant born to mother with uterine cord prolapse via emergency c-section approximately 10 minutes prior to birth. Infant required PPV for 4 minutes after birth and Apgars were 3 and 7. Infant's arterial cord blood gas promising for good outcomes- Why?
pH 7.23
pCO2 70
HCO3 26
Base deficit -4
What is Minimal Metabolic Impact?
Also, pH and base deficit (and Apgar) outside of range for cooling per algorithm
Increased hydroxide ion accumulation causing the body to remove more CO2 and a higher than normal pH
What is Metabolic Alkalosis?
Waste products include CO2, alcohol, and lactic acid
What is Anaerobic Metabolism?
Fetal shut driving blood away from the liver. Most common reason for UVC malposition
What is Ductus Venosus?
Interpret this arterial blood gas:
pH: 7.10
pCO2: 75
HCO3: 22
Base deficit: -10
What is Respiratory Acidosis?
Important action at time of birth to ensure accurate blood gas sample is drawn
What is Double Clamped?
This type of sample will always be more acidotic than its counterpart when drawn from an umbilical cord.
What is Arterial?
ATP generator for the cell
What is Mitochondria?
Diagnosis with clinical features of high pulmonary vascular resistance, increased pCO2, hypoxia, and right to left shunting of blood across the PDA, PFO, or both
What is Persistent Pulmonary Hypertension of the Newborn (PPHN)?
Sample should be sent to lab within this time frame
What is 60 minutes?
Maternal symptom categorizing a delivery as “high risk” according to ACOG because of the effect it has on the Oxyhemoglobin Disassociation Curve.
What is Fever?
Almost always the least important finding when interpreting any kind of blood gas
What is the pO2?
Only process utilized by aerobic and anaerobic metabolism
What is Glycolosis?
Any blood pumped away from the heart
What is Arterial?