This is the single most effective way to prevent the spread of infection in healthcare settings.
What is hand hygiene?
This is the most common cause of fever in travelers returning from sub-Saharan Africa
What is malaria?
This tick is found in Kansas and Missouri and can transmit Ehrlichiosis, Southern Tick-Associated rash illness (STARI) and Heartland virus

CDC
What is the lone star tick (Amblyomma americanum)?
This broad category is the most common identifiable cause of FUO
What are infections?
Very early on in the COVID-19 pandemic (3/12/2020), this star of Forrest Gump and Toy Story announced he had been diagnosed with the virus
Who is Tom Hanks?
Staff entering and airborne isolation room must wear one of these
What is a PAPR (powered air-purifying respirators) or N95 mask?
This flavivirus infection, which can cause jaundice, hemorrhage and high mortality, has a vaccine that is required by some countries prior to travel
What is yellow fever?
A 29 year old who lives in Olathe, KS and currently pregnant at 27 weeks presents with fever and rash on the palms and soles after removing an engorged tick a few days prior. This is the first line treatment

CDC
What is doxycycline?
These are the criteria that can be used to define fever of unknown origin (must name 2)
What is fever >38.3 lasting for extended period without a diagnosis despite a reasonable evaluation (inpatient or outpatient)
Magic Johnson notably announced in 1991 that he had contracted this infectious disease, leading to his retirement from the NBA

Brittanica
What is HIV?
Hands must be washed with soap and water, not sanitizer, after contact with this spore forming organism
What is Clostridium difficile (C. Diff)?
This Aedes mosquito-transmitted viral infection causes severe joint pain, rash and fever, earning the nickname “breakbone fever”
What is dengue fever?
This tick borne bacterial infection, which causes eschar formation and regional lymphadenopathy, has been associated with exposure to rabbits
What is Tularemia (Francisella tularensis)?
These should be included in your differential diagnosis for nosocomial FUO (name 3)
What are: C diff, pneumonia, UTI, DVT/PE, drug induced fever, abscess, blood transfusion reaction, CLABSI?
George Orwell, author of Animal Farm and 1984, died at age 46 due to this infection, the most common infectious cause of death worldwide currently
What is tuberculosis?
Patient presenting with fever, Koplik spots, and rash requires this type of isolation

UpToDate
What are airborne precautions?
This bacterial infection, transmitted by contaminated food or water, presents with fever, relative bradycardia and rose spots
What is typhoid fever (Salmonella typhi)?
Peripheral blood smear showing intracellular parasites in a “Maltese cross” formation suggests this disease
CDC
What is Babesiosis? (Babesia microti most commonly)
This large-vessel vasculitis is a classic cause of FUO in elderly patients
What is temporal (giant cell) arteritis?
Bob Dylan had to cancel a tour in 1997 due to pulmonary infection and pericarditis due to this dimorphic fungi which is commonly seen in KS and MO

Bob Dylan Center
What is Histoplasmosis?
This yeast is associated with high rates of antifungal resistance, can easily spread between patients, and is a major concern for IPAC
What is Candida auris?
A traveler from Central America with myocarditis and megacolon might have this chronic infection transmitted by triatomine beetles (“kissing bugs”)

Texas A&M
What is Chagas disease (Trypansoma cruzi)?
This illness can occur after a being bitten by the lone star tick and cause patients to have a urticaria, nausea, vomiting, abdominal pain after eating red meat
What is Alpha-gal syndrome?
This pathogen causes culture negative endocarditis and has been associated with cat exposure
What is Bartonella henselae?
In Mary Poppins, the song “A Spoonful of Sugar” was inspired by the writer taking the oral vaccine (with a sugar cube) for this virus, which was eradicated from the US in 1979
What is polio?