B cell Development
The site where B cells develop in humans
bone marrow
The site where T cells complete their development.
thymus
This degrades intracellular antigens into peptide fragments
proteasome
This test uses an enzyme-linked antibody to detect proteins or antigens in a sample.
ELISA
In Toy Story 4, what object is Forky originally made from?
a spork
he enzyme required for V(D)J recombination in B cells.
RAG
T cells are “restricted” to recognizing antigen only when it’s presented by this molecule.
MHC
This catalyzes the removal of CLIP from MHC II
HLA-DM
This assay counts the number of infectious viral particles by observing cell destruction.
Viral plaque assay
In Spiderman: No Way Home, which actors return to reprise their roles alongside Tom Holland?
Tobey Maguire and Andrew Garfield
Immature B cells are tested for this before leaving the bone marrow.
self-reactivity
Positive selection in the thymus ensures T cells can bind to these molecules.
self-MHC
These proteins function to stabilize MHC I as its chains are assembled
calnexin & calreticulin
This rapid diagnostic test uses capillary action across a strip to detect antigens or antibodies.
lateral flow assay
In Frozen II, Elsa hears a mysterious voice calling her where?
into the unknown
The process by which B cells switch from making IgM to IgG.
Isotype switching
Negative selection eliminates T cells that do this too strongly.
Bind self antigen
This pulls MHC I closer to TAP
tapasin
This classic assay measures the concentration of specific proteins by observing rings in a gel.
radial immunodiffusion
In Super Mario Brothers Movie (2023), who voices Mario?
Chris Pratt
This mechanism improves antibody affinity after B cell activation.
somatic hypermutation
A defect in this transcription factor leads to autoimmunity
AIRE
This is what cross-presentation of viral antigens in DCs accomplishes
presentation of viral peptides on MHC I and II
In an ELISA, a stronger color change means this about the antigen concentration.
duh, chatGPT!
In Guardians of the Galaxy (2014), which classic 70's song does Star Lord dance to at the beginning of the movie?
"Come and get your love" by Redbone