ABO
N-acetyl-D-galactosamine is the immunodominant carbohydrate that reacts with:
A: Arachis hypogaea; B: Salivia sclarea; C: Dolichos biflorus; D: Ulex europeaus
What is C, Dolichos biflorus?
Autoantibodies affect compatibility testing with:
A: no affect; B: pos. DAT; C: ABO, Rh, antibody screen, crossmatching may show abnormal results; D: results depend on autoantibody specificity
What is C, ABO, Rh, antibody screen, and crossmatching may show abnormal results?
Marker indicating immunity to hepatitis B infection.
A: Anti-HBc IgM; B: HBsAg; C: Anti-HBs; D: Anti-HBc IgG
What is C, Anti-HBs?
Kernicterus is caused by the effects of:
A: anemia; B: unconjugated bilirubin; C: antibody specificity; D: antibody titer
What is B, unconjugated bilirubin?
Preliminary evaluation of a transfusion reaction includes all of the following, except:
A: check pre- & post-txn samples for color of serum; B: perform ABO & Rh recheck; C: perform DAT on post-txn sample; D: perform panel on pre- & post-txn samples
What is D, perform a panel on pre- and post-transfusion samples?
Acquired B antigens have been found in:
A: Bombay phenotype individuals; B: Group O persons; C: Persons of all blood groups; D: Group A persons
What is D, Group A persons?
A recipient sample must be kept in the blood bank for this many days after compatibility testing:
A: 3 days; B: 5 days; C: 7 days; D: 10 days
What is C, 7 days?
All of the following are required tests on donor blood, except:
A: HBsAg; B: Anti-CMV; C: HIV-1; D: Anti-HTLV I/II
What is B, anti-CMV?
Testing done for an exchange transfusion when the mother's serum contains an alloantibody is:
A: XM & AS; B: ABO, Rh, AS, & XM; C: ABO, Rh, & AS; D: ABO & Rh only
What is B, ABO, Rh, AS & XM?
Most likely cause of a hemolytic reaction to blood transfused 8 days ago:
A: immediate, nonimmunologic from volume overload; B: delayed immunologic from antibody such as anti-Jka; C: delayed immunologic from iron overload; D: immediate, immunologic from clerical error/ABO incompatibility
What is B, delayed immunology from an antibody such as anti-Jka?
The blood group with the least amount of H antigen:
A: A1B; B: A2; C: B; D: A1
What is A, A1B?
Crossmatching protocol for platelets and/or plasma is:
A: Perform a reverse grouping on donor plasma; B: no testing required; C: perform reverse grouping on recipient plasma; D: platelets must be HLA compatible
What is B, no test is required?
Nucleic acid testing (NAT) is performed to detect which viruses:
A: HIV & HTLV-1; B: HTLV I/II; C: HIV, HCV, HBV, Zika and WNV; D: HIV, HBV, WNV
What is C, HIV, HCV, HBV, Zika, and WNV?
All of the following are routinly performed on a cord blood sample, except:
A: forward ABO typing; B: AS; C: Rh typing; D: DAT
What is B, antibody screen?
This may be found in serum of a person exhibiting signs of TRALI (txn-related acute lung injury):
A: RBC alloantibody; B: IgA antibody; C: antileukocyte antibody; D: allergen
What is C, antileukocyte antibody?
If all forward and reverse ABO results, and autocontrol, are positive, this should be done:
A: wash the cells w/ warm saline & autoadsorb serum at 4C; B: retype sample w/ different reagent lot; C: use polyclonal reagents; D: report sample as group AB
What is A; Wash the cells with warm saline, and autoadsorb the serum at 4C?
Incompatible donor unit is found to have a positive DAT, this should be done with the unit:
A: discard unit; B: antigen type unit for high-frequency antigens; C: wash donor cells and use washed cells for testing; D: perform a panel on incompatible unit
What is A, discard the unit?
Unit tests positive for syphilis with rapid plasma reagin (RPR) test. Treponema pallidum particle agglutination (TP-PA) test is negative on same unit. The disposition of the unit is:
A: unit may be used to prep components; B: donor must be contacted & questioned further; if RPR test result is most likely false pos, unit may be used; C: unit must be discarded; D: cellular components may be prepared but must be irradiated
What is A, the unit may be used to prepare components?
If HDFN is caused by maternal anti-K, then:
A: give Kell immune globulin; B: monitor mother's Ab level; C: prevent formation of K-pos cells in fetus; D: not a problem - anti-K not known to cause HDFN
What is B, monitor the mother's antibody level?
This occurs in ~1% of all txns - temp rises greater than 1C above 37C and is associated with blood component txn, not patient's medical condition:
A: immediate hemolytic; B: delayed hemolytic; C: febrile nonhemolytic reaction; D: TRALI
What is C, febrile nonhemolytic reaction?
Type of RBCs that can be transfused to an A2 person with anti-A1:
A: A only; B: A or O; C: B; D: AB
What is B, A or O?
Donor was found to contain anti-K using pilot tubes. The compatibility test will be affected by:
A: AHG major crossmatch would be pos.; B: IS major crossmatch would be pos.; C: recipient's antibody screen would be pos. for anti-K; D: compatibility testing would not be affected
What is D, compatibility testing would not be affected?
The tests affected by daratumamab (Darzalex) in a multiple myeloma patient and the typical recommendations for transfusion are:
A: antibody screen/least incompatible RBCs; B: ABO/washed RBCs; C: Rh/leukocyte-poor RBCs; D: All of the above
What is A, antibody screen/least incompatible RBCs?
Rh-negative women can have a positive antibody screen compared with Rh-positive women of childbearing age because:
A: formation of active anti-D; B: received RhIg; C: formed anti-K; D: higher rate of transfusion
What is B, they have received RhIg (passive anti-D)?
Result of group A blood given to group O patient is:
A: nonimmune txn reaction; B: immediate hemolytic txn reaction; C: delayed hemolytic txn reaction; D: febrile nonhemolytic txn reaction
What is B, immediate hemolytic transfusion reaction?