GI
Neurology
Hemonc
Name that antibody
Glandz
100

This procedure removes a portion of the stomach, thus placing the patient at risk for vitamin B12 deficiency.

What is gastrectomy

100

In dementia with lewy bodies these group of medications can worsen visual hallucinations and can lead to balance impairment and falls

What are antipsychotics? 

100

This diagnosis is confirmed by bone marrow aspiration showing >20% myeloblasts

What is acute myelogenous leukemia?

100

This disease has positive anti U1 RNP antibodies

What is mixed connective tissue disease?

100

This insulin is ideal for steroid-induced hyperglycemia

What is NPH?
200

Recurrent pancreatitis + elevated IgG4 + "sausage shaped" pancreas on CT

What is autoimmune pancreatitis

200

Sac-like structure protrudes through a vertebral defect containing meninges, spinal cord, and CFS

What is meningomyelocele?

200

This common agent used in breast cancer treatment causes reversible non-dose related heart failure

What is Trastuzumab (Herceptin)?
200

These are 3 indications to initiate Allopurinol for Gout prophylaxis

What is

1) Disabling and frequent gout attacks (2 or more - although based on discussion can initiate at lower)

2) Tophi and structure joint damage 

3) Gout with renal insufficiency

200
This is the most common cause of adrenal insufficiency

What is exogenous steroids?

(Look out for oral, injectable and inhaled steroids)

300

Barrett's esophagus is characterized by this type of change.

What is columnar epithelium replaces the stratified squamous epithelium that normally lines the distal esophagus

300

Unilateral facial weakness, facial droop and diminished eye blink

What is Bell's Palsy?

300

Once a colonoscopy is done, these 2 tests are further required to stage colorectal cancer?

What is CT Chest/Abdomen/Pelvis and serum CEA?
300

This is the serum uric acid goal for patients receiving urate-lowering therapy in gout

What is <6 mg/dL


(Extra: <5 mg/dL with tophi)

300

This is the first line treatment for acromegaly secondary to a GH-secreting pituitary adenoma

What is surgery?

400

Celiac disease is associated with these two HLA variants.

What are HLA DQ1 and DQ8

400

What breathing pattern is expected with damage to the cortex?

What is Cheynes-Stokes respirations?

400

Daily Double!

Capecitabine (Xeloda) is an oral prodrug of 5-FU which is used in the treatment of colon cancer and can cause this obscure cutaneous reaction that could impair criminal investigation


What is loss of fingerprints?

JAMA Oncology says temporary, returns 2-4 weeks after cessation of drug

400

34F history of SLE on HCQ, mycophenolate and prednisone who presents with 6-month history of gradually increasing pain in the left groin with some radiation to the left buttock, particularly with stair climbing

What is glucocorticoid-induced osteonecrosis?

SLE + steroids are risk factors

Present with groin pain radiating to the buttocks which worsens with ambulation

400

50M with history of colonic polyps, pre-diabetes, HTN presents with facial pain, fatigue and low libido

What is acromegaly?

500

Sitophobia + weight loss + epigastric bruit

What is median arcuate ligament syndrome

500

In patients with gastric by-pass surgery this element deficiency can lead to progressive myelopathy similar to VIT B12 deficiency

What is copper?

500

Patients with Stage III rectal cancer should be given this treatment modality which would not be given to patients with Stage III colon cancer

What is radiotherapy?

500

Daily Double!

Match the following antibodies to their conditions

Anti-Jo1

Anti-histone

Anti-centromere

Anti-Sm

(Not an antibody) HLA-B27

What is


Anti-Jo1 > poly/dermatomyositis

Anti-histone > drug-induced lupus

Anti-centromere > CREST syndrome

Anti-Sm > SLE

HLA-B27 > strong association with ankylosing spondylitis, weaker with psoriatic arthritis (either is acceptable)

500

You follow up with patient 1 year post transsphenoidal resection of pituitary mass and IGF level remains elevated, next step therapeutically?

What is a Somatostatin analogue?


+ practically might repeat brain MRI and repeat resection...

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