It Hurts to Pee
What are the indications to screen & treat asymptomatic bacteruria?
Pregnancy & patients undergoing urological procedures
Most commonly implicated pathogen in bacterial septic arthritis among young adults/ adolescents
N. gonorrhoeae
Most common cause of acute gastroenteritis in adults
Norovirus
Diagnostic test for Lyme disease
ELISA and Western Blot
Most common post-transplant viral infection.
CMV
What are the 3 first-line antibiotics (including duration) for acute uncomplicated cystitis?
Nitrofurantoin 100 bid x5d
Bactrim DS 160/800 bid x3d
Fosfomycin 3g single dose
Most sensitive and specific imaging modality for diagnosis of osteomyelitis
MRI
Define acute, subacute, and chronic diarrhea
<14d, 14-30d, >30d
Peripheral blood smear with merozoites arranged in tetrads
Babesiosis (Maltese cross)
Name the treatment of TB in the early 20th century involving separation of lung from pleura
Plombage / pneumonolysis
When would prophylactic daily or post-coital antibiotic therapy be indicated?
Women who have had 3 or more UTIs in past 12mo, or 2 or more in last 6mo
Most common pathogen associated with osteomyelitis in patients with sickle cell disease
Salmonella
Most common cause of hospital acquired infectious diarrhea
C diff
Vector for Rocky Mountain Spotted Fever
American Dog Tick, Rocky Mountain Wood Tick, Lone Star Tick
Describe the components of CURB-65
Confusion, BUN>19m RR>30, SBP<90 or DBP<60, Age 65+
Name 2 outpatient treatment options (including duration) for acute, uncomplicated pyelonephritis.
Ciprofloxacin 500 bid x7d
Levofloxacin 750 daily x5d
Bactrim DS bid x14d
Beta-lactam x10-14d
Duration of antibiotics for osteomyelitis
At least 4 to 6 weeks
Per IDSA guidelines, define severe and fulminant C Diff Infection
Severe: Cr >1.5 or WBC >15,000
Fulminant: hypotension or shock, ileus, or megacolon
High fever, rash, leukopenia, thrombocytopenia, elevated transaminases
Ehrlichia/Anaplasmosis
Name 3 arboviruses.
Chikungunya, Dengue, Japanese encephalitis, West Nile, Zika, Yellow Fever, African Swine Fever
Distinguish between a UTI relapse vs reinfection.
Relapse: same bacteria within 2 weeks after susceptible therapy
Reinfection: different organism causing UTI or the same organism but > 2 weeks since prior treatment
Name an antibiotic regimen to treat an MSSA hardware-associated joint infection
Nafcillin / Cefazolin / Ceftriaxone plus Rifampin
How should you treat diarrhea caused by E coli O157:H7?
Supportive care for EHEC (STEC). Antibiotics increase risk of HUS.
Name 3 complications (different organ systems) of early disseminated lyme disease
Cutaneous: erythema migrans
Ocular: conjunctivitis, uveitis, keratitis
Neuro: aseptic lymphocytic meningitis, facial nerve palsy, encephalitis
Cardiac: AV block
Infectious cause of rapidly progressive and fatal dementia and ataxia
Prion disease