Antibacterial Drugs
Foodborne diseases
Tropical Infection
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Fungal Infections
100
The bioavailability of this antibiotic reduced x 50 percent if taken with food and the absorption of this drug decreased with administration of chelating multivalent cations (ie, aluminum, calcium, iron, magnesium)
What is tetracyclines?
100
Treatment of this infection is primarily supportive; antibiotics and antimotility agents may increase the risk of developing hemolytic uremic syndrome and do not appear to shorten the duration of infection.
What is the treatment of EHEC 0157:H7?
100
It is a tick-borne disease. Asplenic persons, the elderly, and persons receiving immunosuppressive drugs are at higher risk for complication.
What is Babesiosis?
100
25 yo male with 2 days of fever and rash. The rash was predominantly on his hands. He had similar episode about a year before, at which time he also had an oral ulcer.
The most likely diagnosis is acute HSV
100
Meningitis with this fungal infection can increase intracranial pressure
What is the classic sign in cerebrospinal fluid analysis in patient with cryptococcal meningitis?
200
It is MAO inhibitor, interacts with SSRIs, tramadol and other drugs to cause serotonin syndrome
What is Linezolid ?
200
Patients with iron overload states, including hemochromatosis, are at increased risk for infection (including bacteremia)
Who is at increased risk of infection with Yersinia species?
200
This parasite replicate at the site of the insect bite and produce slow-healing or nonhealing painless nodules or, more commonly, ulcers with heaped-up edges
What is Cutaneous Leishmaniasis?
200
28 yr old man had a witnessed gran mal seizure ,was hospitalized and found to have a cerebral mass on MRI concerning for a neoplasm or brain abscess. Sinusitis was diagnosed , based on sinus pain and MRI findings. He was started on vancomycin, metronidazole, cefepime and phenytoin. About a week later he developed a temperature of 40C and a rash that soon spread over about half his body. The rash became bullous and associated with conjunctivitis and pain on swallowing. Hypotension requiring fluid resuscitation and azotemia occurred
The most likely diagnosis is toxic epidermal necrolysis.
200
Most serious form of this infection, most often occurs in immunosuppressed patients who are neutropenic or are hematopoietic stem cell transplant recipients
Who are at risk of invasive pulmonary aspergillosis?
300
Bone marrow suppression and hyperkalemia can be seen when this antibiotics is giving with higher doses
What is a side effect of Trimethoprim–sulfamethoxazole (TMP–SMX)?
300
Illness is usually self-limited, although bacteremia with extraintestinal infection (involving vascular endothelium, joints, or meninges) may occur
What is the prognosis of Nontyphoidal Salmonella?
300
It causes enteric fever in persons who ingest fecally contaminated food or water. The risk is highest for travelers to the Indian subcontinent, Southeast Asia, Africa, and Latin America.
What is Typhoid?
Caused by Salmonella enterica serotype Typhi (S. typhi) and serotype Paratyphi (S. paratyphi)
300
Which of the following is the most likely diagnosis for these findings demonstrate?
Sporotrichosis.
300
The characteristic appearance of this fungus is
broad, nonseptate hyphae with acute-angle branches.
What is the characteristic appearance of Mucormycosis (formerly zygomycosis)?
400
This class of drugs Inhibits DNA gyrases (topoisomerase II and IV) which are required for bacterial DNA replication, transcription, repair, and recombination
What is the mechanism of action of Fluoroquinolones?
400
Infection with this bacteria can cause septicemia and necrotizing skin infections in patients who have liver disease.
What is the clinical manifestation of Vibrio parahaemolyticus?
400
The transmission of this infection occurs by contact of skin or mucous membranes with fresh water or moist soil contaminated with the urine of rodents and other mammals
How does the transmission of leptospirosis occur?
400
This cerebrospinal fluid Gram stain specimen from a patient with fever and a stiff neck shows findings characteristic of which of the following
What is Streptococcus pneumonia?
400
Lab evaluation with this evaluation will show pancytopenia and transaminitis (possible clue: AST > ALT) with elevated alkaline phosphatase; diffuse reticulonodular (miliary) infiltrates on imaging.
What are the lab finding in histoplasmosis?
500
This antibiotic has gram-negative and gram-positive activity (including methicillin-resistant S. aureus and vancomycin-resistant Enterobacteriaceae) and achieves high concentrations in the urine, making it useful for treating cystitis.
Which bacteria does Fosfomycin cover?
500
Nitazoxanide also can be considered when supportive care does not result in symptom resolution.
What is the treatment of Cryptosporidium infection?
500
Chronic infection with this parasite causes cardiomyopathy that causes congestive heart failure, sudden cardiac death, arrhythmias, and heart block
What is Chagas Disease?
500
African‐American male with HIV, lost to followup, last CD4=4. VL 99,000 seeks attention for nonpruritic rash on his chest and head of several weeks
What is cryptococcus neoformans?
500
Treatment requires reversal of any predisposing condition, extensive surgical removal of affected tissue, and early antifungal therapy.
What is the treatment for Mucormycosis ?