Adipokines
What is one type of Adipokine from the presentation?
Leptin/Adiponectin/SFRP5
Are Cytokines pro- or anti-inflammatory?
Pro-Inflammatory
Name a diet that was mentioned in the presentation that can prevent Chronic Low-Grade Inflammation.
Mediterranean diet
Name one way that causes Chronic Low-Grade Inflammation.
Obesity + Adipose Tissue/Immune Cell Infiltration/Cytokine Production/Self-Inducing Inflammation
What hormones effectiveness is altered by chronic inflammation?
Insulin
What adipokine fights inflammation, but is less common in people w/ obesity
Adiponectin
Pro-Inflammatory cytokine that is elevated during chronic inflammation
TNF-alpha
What type of fat is reduced with regular exercise?
visceral fat
How many macrophages are present in Immune Cell Infiltration?
1 (M1)
What stores fat and becomes inflamed in obesity?
Adipose tissue
What chemokine (or signal) recruits immune cells into fat tissue?
MCP-1
What do M1 macrophages form in obese adipose tissue?
Crown-like structures
What is one lifestyle change that lowers TLR expression, while also improving immune function?
Name all three cytokines that impair insulin signaling.
TNF-alpha, IL-6, and IL-1beta
Which immune cell becomes exhausted in chronic inflammation?
T-cells or Immune cells