When giving tetracycline you know that you should not give to which groups (name two groups)
What is
What is pregnant women (2nd and 3rd trimesters) and young children under 8, will stain their teeth by binding to calcium
100
Indications for biventricular pacemaker-defibrillator placement include NYHA class III or IV heart failure, a QRS width greater than 120 msec, and an ejection fraction less than or equal to this percent
What is
35%
100
Applies positive pressure at end of expiration. Decreases intra-pulmonic shunting. Decreases need for high FiO2 (opens alveoli)
What is
What is PEEP
100
*Clinical signs or symptoms of DVT
*Alternative diagnosis less likely than PE
*Heart rate 100 beats per minute
*Immobilization (>3 days)
or surgery in last 4 weeks
*Previous history of DVT or PE
*Hemoptysis
*Active cancer within the last 6 months
What is
Well's Criteria
100
Name the 2 antibodies that are highly SPECIFIC for SLE
What is
Anti-dsDNA and Anti-Smith
200
Which adverse reactions is noted with gentamicin
(there are at least 4 - name 2)
What is
Neurotoxicity
Nephrotoxicity
ototoxicity
Neuromuscle blockade
200
Exercise stress testing is only diagnostic at an adequate workload, defined as achieving this percent of the maximum predicted heart rate
What is
85%
200
Two methods to determine severity of PNA
What is:
PSI and CURB-65
200
■ Stage 0: no diagnosis but at risk with chronic cough and sputum production present but with normal spirometry.
■ Stage I: mild COPD characterized by mild airflow limitation (FEV1/FVC less than 70% but FEV1 80% or more than predicted).
■ Stage II: moderate COPD, indicated by worsening airflow limitation (FEV1 50-79% predicted) and usually progression of symptoms, with shortness of breath on exertion.
■ Stage III: severe COPD characterized by further worsening of airflow limitation (FEV1 30-50% predicted), increased shortness of breath, and repeated exacerbations.
■ Stage IV: very severe COPD with severe airflow limitation (FEV1 less than 30% predicted) or the presence of chronic respiratory failure.
What is
GOLD's Criteria for COPD
200
Please name 4 of the 7 Rheumatologic diseases with positive ANA (SENSITIVE)
What is
RA, SLE, Drug-induced SLE, MCTD, limited&diffuse systemic sclerosis, Sjogren's, Polymyositis/Dermatomyositis
300
What great anti-MRSA drug can't be used in lung infections and must explain why (pathophysiology)
What is
Daptomycin
surfactant inhibits drug
300
Which statin lowers the LDL the most (most bioavail/potent)?
Which has fewest side-effects?
What is
Rosuvastatin lowers LDL the most.
Pravastatin fewest side-effects and safest in liver disease
300
Diagnostic criteria for ARDS
What is
INCLUSION CRITERIA: Acute onset of:
*PaO2/FiO2≤ 300
*Bilateral (patchy, diffuse, or homogeneous) infiltrates consistent with pulmonary edema
*No clinical evidence of left atrial hypertension (CHF exacerbation)
300
*AGE
*Creatinine
*ASA Class
*Preoperative Functional Status
*Procedure type/site
What is
Gupta Perioperative Cardiac Risk
300
Which Anti-Neutrophil Cytoplasmic Antibody is very SPECIFIC for Granulomatosis with Polyangitis (GPA -formerly known as Wegener's granulomatosis)
What is
c-ANCA
What is the difference between p-ANCA and c-ANCA (immunofluorescence pattern)
- Follow up with Anti-PR3 and anti-MPO ELISA
400
Aminoglycosides(gentamicin) pharmacodynamics act how on the bacterial cell
What is
binding to the 30s ribosomal subunit, this leads to misreading the information used in the cell to form proteins-then amino acid do not link correctly
400
Sometimes mistaken for ischemic ST elevation in the anteroseptal leads, this syndrome is a relatively rare but significant cause of sudden cardiac death, particularly in males of Southeast Asian descent (Laos/Thailand)
What is
Brugada Syndrome
400
Ideal Ventilator settings for ARDS patient. Looking for 2 settings specifically (I want numbers - think volumes/pressures)
What is
6ml/kg tidal volume (predicted body weight)
plateau pressure <30 cm H20
What is
The Pulmonary Embolism Severity Index (PESI)
400
___anti-body very SENSITIVE for Rheumatoid Arthritis, where ____anti-body is very SPECIFIC for Rheumatoid Arthritis
What is
1.) Rheumatoid Factor (RF)
2.) anti-Citrullinated cyclic peptide (anti-CCP)
** patient with both usually has poorer prognosis with extra-articular manifestations - nodules and lung involvement
500
Name the drug and generation it is in of the cephalosporins that can't be used against Pseudomonas, but is only cephalosporin that covers MRSA - specially skin infections
What is
Ceftaroline
5th Generation
500
What class of Antiarrhythmic drugs do we not use in patients status post MI/structural heart disease - increase mortality
Per the CAST I and CAST II trials
(Name class and at least one of the drugs in the class)
What is
Class IC: Flecainide, Propafenone, Morcizine
500
Vasopressor:
*No increased HR (good when tachyarrhythmias limit use of other pressors)
*Selective alpha-1 adrenergic agonist
*More limited study for use in sepsis (surgeons love it for blood loss hypovolemic shock)
*Rapid onset/short duration