Stem Cells
This type of stem cell is found in a fully developed organism rather than in an embryo.
Replaces Thymidine and, with the use of antibodies, is a marker for synthesized DNA
What is BrdU?
When a planarian starts to heal after being cut, it grows this small pale bump og new tissue at the wound site to regenerate.
What is a blastema?
As irradiation dosage increases, this happens to SMEDWI-1 levels and the number of neoblast colonies.
What is they both decrease?
A cool thing that humans can regenerate.
What are finger tips?
Have the ability to self renew.
What are stem cells?
Decreases division and allows researchers to test if the stem cells are pluripotent.
What is ionizing radiation?
A single transplanted cell in a planarian has the ability to regenerate this much of the organism.
What is an entire one?
Makers that show cell differentiation.
What are gata 4/5/6 and chat?
This animal is the acronym for fluorescent tagging used on the SMEDWI-1 gene.
What is FISH?
A characteristic that describes the ability of a stem cell to be able to produce different kinds of cells.
What is pluripotent?
Act as an internal blueprint for muscle tissue in planarians.
What are Position Control Genes?
The gene that is expressed in all adult neoblast and served as the primary marker for planarian stem cells.
What is SMEDWI-1
This is what the distribution of SMEDWI-1 throughout a planarian shows about its stem cells.
What is that stem cells are distributed throughout the body and are capable of regenerating different cell types?
This disease can be treated with regenerative medicine.
What is Alzheimers disease?
Regeneration of planarians occur from this many stem cells.
What is one stem cell?
This is why the irradiation dose must be carefully controlled in an experiment.
What is using enough radiation to cause measurable damage, but not so much that it kills the cells or prevents regeneration?
The three germ layers.
Researchers identified the locations of C. Neoblasts to transplant for single cell transplantation.
What is Hoest staining and SS and FS?
These are the pathways that humans use to regenerate their finger tips.
What are Wnt, FGF, and BMP?
These stem cells are not lineage restricted.
What are totipotent cells?
cDNA probe hybridizes RNA strand and highlights the gene
What is in situ hybridization?
Planarians are known for having adult stem cells called neoblasts that are described as this type, meaning a single one has the power to turn every kind of cell in the planarians body.
What is pluripotent?
Regeneration occurs from the transplanted C. Neoblast by doing this.
What is differentiated SNPs?
The regeneration used by crabs and lobsters that grow in place of another body part.
What is Heteromorphosis?