Immunology
The organ that T cells mature
What is the thymus?
The subunits of adult hemoglobin (HbA1)
What is alpha2beta2?
The gram positive cocci that is catalase positive and coagulase positive
What is S aureus?
The rotator cuff muscles
What are supraspinatus, infraspinatus, teres minor, subscapularis?
The MHC that binds CD4 and TCR
What is MHC II?
The disorder with the inhibition or deficiency of ADAMTS13 (vWF metalloprotease)
What is thrombotic thrombocytopenic purpura (TTP)?
The virus of the "kissing disease" that infects B cells through CD21
What is EBV?
The MSK test involving flexion and extension of the knee with rotation of the tibia/foot, examining pain and popping of medial (upon external rotation) vs. lateral meniscal tears (upon internal rotation)
What is the McMurray test?
The hypersensitivity reaction with an immune complex (antigen-antibody) that activates complement
What is Type III hypersensitivity?
Overproduction of IgM resulting in peripheral neuropathy and hyperviscosity syndrome, but no CRAB findings (hypercalcemia, renal involvement, anemia, bone lytic lesions)
What is Waldenstrom macroglobulinemia?
The virus binds CD4 and a coreceptor, either CCR5 on macrophages or CXCR4 on T cells
What is HIV?
The most commonly fractured carpal bone
What is the scaphoid?
Double positive (CD4+/CD8+) T cells expressing TCRs capable of binding self-MHC on cortical epithelial cells survive
What is positive selection?
The chromosomal translocation associated with APL
The top bugs that cause pelvic inflammatory disease
What is Chlamydia trachomatis and Neisseria gonorrhoeae?
The MSK condition characterized by arm hanging by side, medially rotated, extended, and pronated
What is Erb palsy ("waiter's tip")?
T cells in the thymic medulla expressing TCRs with high affinity for self antigens undergo apoptosis or become regulatory T cells
What is negative selection?
What is CD20?
The flulike symptoms after antibiotics are started due to host response to sudden release of bacterial antigens (typically after treatment of spirochetal infections)
What is Jarisch-Herxheimer reaction?
The systemic chronic inflammatory disease affecting MCP, PIP, and wrist only (not DIP or 1st CMC)
What is rheumatoid arthritis?