Dylan
Dylan's work focuses on what lineage of macrophage?
What is bone marrow derived?
The chromosomal location of TSC22D3?
What is the X chromosome?
What is the origin(s) of Tissue-resident macrophages (TRM’s)?
What is the transmembrane receptor that binds growth factors and enhances growth and survival of breast cancer
What is “HER2” -or- “human epidermal growth factor receptor 2”
What is the goal of vaccinating mice?
What is to produce antibodies
This known activator of macrophages inspired Dylan's work
What is Lipopolysaccharide (LPS)
What is the instrument used to create low oxygen conditions for cell cultures?
What is a hypoxia chamber?
What are the receptors responsible for T cell activation in the macrophages?
Background strain for d16HER2 mice
What is FVB
Name at least two methods of euthanasia in mice
What markers does Dylan's work investigate?
What is CD80, CD86, MHC I, MHC II, F4/80, and CD85k?
What reagent is used during transfection to encapsulate DNA?
What is lipofectamine?
What is the full name of LILRB4?
What is leukocyte immunoglobulin-like receptor B4
Background strains that make up Diversity Outbred mice
What are (any 4 of); 129, A/J, C57BL/6 (B6 accepted), CAST, NOD, NZO, PWK, WSB
Why are transfected cells often plated with antibiotics?
What is to keep the plasmid which provides antibiotic resistance to the cell?
Dylan's work uses primarily this background of mouse
What is B6
What restriction enzymes are used to cut the TSC22D3 insert?
What is SgfI & MluI?
Why are Natural killer (NK) cells part of the innate immune system?
What is they don't have antigen-specific receptors.
Why is using Diversity Outbred mice important?
What is they mimic human diversity
What assay utilizes a "sandwich" of antibodies to look at IFN-gamma secretion by T cells?
What is Elispot
Dylan's work is this kind of study
What is de novo
What is the purpose of a leucine zipper structure?
In which part of the mouse did I inject the TC-1 cell line?
What is the tail vein
What does GEMM stand for?
What is “Genetically engineered mouse model”
What genotype is a "unicorn" mouse?