Data Sources
What publication data sources are we integrated with?
Pubmed and ArXiv
What is a pharmaceutical?
A pharmaceutical is any kind of compound manufactured for use as a medicinal drug, like cough syrup or sleeping pills.
What is a medical device?
A medical device is any device intended to be used for medical purposes. Medical devices benefit patients by helping health care providers diagnose and treat patients and helping patients overcome sickness or disease, improving their quality of life.
What is in Nebula's AI processing tech stack?
Automatic semantic expansion, Natural Language Processing (NLP), Optical Character Recognition (OCR), Multiple Ontologies (i.e. DBpedia Spotlight), Image Recognition, and Audio Transcription
What is the difference between an Assignee & Applicant?
Assignees are the legal IP rights holders of the patent. Applicants are the individuals or entities who filed the patent application.
What Grant data sources are we integrated with?
Grants.gov, SBIR, NIH Reporter, Wellcome, Horizon 2020, and NSF.
What is a drug indication?
In medical terminology, an "indication" for a drug refers to the use of that drug for treating a particular disease. For example, diabetes is an indication for insulin.
The Food and Drug Administration (FDA) classifies indications for drugs in the United States. Indications for drugs can be classified in two categories:
What does R&D do?
They are design engineers. Their role involves researching, designing, testing, and modifying technical designs for various medical devices before they are manufactured. They provide the scientific direction and early-stage development. They can significantly reduce costs by minimizing product risk, expediting time to market, improving organizational resources, and restructuring a company's use of resources
How is AI important? Name 1 application for AI for ResoluteAI researchers.
Artificial Intelligence enhances the speed, precision and effectiveness of human efforts.
What are forward citations an indication for?
Strength of patent.
4 Part Question:
What Patent data sources are we integrated with? How many university tech transfer offices are we integrated with? What kind of information can you find on Crunchbase? How many news providers and languages are provided on the news database?
USPTO, EPO (European Patent Office), and WIPO (World Intellectual Property Organization). Over 300. Business information about private and public companies. Over 10,000 news providers in 42 languages.
What are the six key elements for medical affairs in product launch planning?
Early scientific and evidence leadership. Organizational knowledge building and performance optimization. Coordinated & needs-based external stakeholder engagement. Scenario planning and lifecycle management. Impact and pull through (Identifying risks and issues. MA-specific KPI framework to capture voice of customer). Executing the right things, well (Solve known problems, program management to drive critical projects, cross-function communication planning: Global-Region-Country)
What does someone in Medical Affairs do?
Medical affairs provides scientific support for late-stage development and post market support for devices. In small companies, the same team may be responsible for both kinds of activities.
They usually function alongside marketing, to provide technical support to both internal teams and external customers.
Manage relationships with key thought leaders and stakeholders
Speed test. Name the 5 largest patent holders in the field of AI. Name the 5 most talked about companies (mentioned in news articles).
Microsoft, Tensorflow, Alphabet, Amazon, and Google.
What are Medical Device Product Codes used for?
Classification product codes are used for internal tracking purposes, such as adverse event monitoring or compliance actions. Product codes may be created and assigned for these purposes.
What countries do we have clinical trial data for?
USA (clinicaltrials.gov), Japan (UMIN-CTR), Australia (ANZCTR), Korea (CRIS), Thailand (TCTR), EU (EUCTR)
Aditx, AstraZeneca, Alexion, Merck, Zentiva, Chinook Therapeutics, and Abbvie
Name all of our medical device clients.
Danaher, Thermo Fisher, Baxter, WL Gore, ConvaTec.
There are many use cases in business, science, and law where the search query may be long and complex and the user is looking for similar documents. Name at least 3 use cases that CaTs can help with.
Comparing patent claims, Identifying similarities in grant abstracts, Research on medical literature, Analyzing the text in financial statements, Comparing regulatory frameworks across jurisdictions, Understanding legal contracts
ResoluteAI built a locality-sensitive hashing algorithm on top of BERT, in an effort to meet our clients needs for better results on long search queries. This technology was released in May - it’s called Conceptual Attribute Search or CAtS
Why is innovation important in life science?
Continuous innovation is one of the pharmaceutical/medical device industry's most defining characteristics. New medications/devices can be crucial for maintaining the quality of human life, and may even affect its duration.
What FDA data sources are we integrated with?
FAERS, FDA Label Repository, Drugs@FDA, MAUDE, Recall Enterprise System (RES), and Device Recalls.
Describe the phases within the early discovery and development process of a new drug.
Early discovery (2 - 5 years, avg $4MM): Target Identification, Target Validation, and Target selection (1 - 3 years). Target to Lead (1 year). Lead to Candidate (1 - 3 years).
Development (5 - 10 years, avg $40MM): Preclinical development (1 - 2 years). Phase 1 FTIH (First time in humans). Phase 2 PoC (Proof of concept). Phase 3 Multicenter trials. Phase 4 Postmarketing surveillance.
What are the 5 phases in the development of a new medical device?
Phase 1: Initiation opportunity and risk analysis. Phase 2: Formulation concept and feasibility. Phase 3: Design and development / verification and validation. Phase 4: Final validation/product launch preparation. Phase 5: Product launch and post launch assessment.
What is a neural network? Bonus points: what are the most popular transformers (A transformer is a deep learning model primarily used in the NLP field)
Neural networks are a set of algorithms, modeled loosely after the human brain, that are designed to recognize patterns. They interpret sensory data through a kind of machine perception, labeling or clustering raw input. ... Neural networks help us cluster and classify.
BERT (Google), GPT-3 (OpenAI), Turing NLG (Microsoft), Megatron (Nvidia)
What is post market surveillance and the purpose of the role?
Post market surveillance, is the practice of monitoring the safety of a pharmaceutical drug or medical device after it has been released on the market and is an important part of the science of pharmacovigilance.
They're purpose is to assess safety and effectiveness of devices that have undergone limited pre-market testing, or to obtain more information on device performance in real-world clinical practice.