List reasons that can impair healing of an ulcer.
Tobacco
Weight
Poor dietary intake
Uncontrolled DM
Poor circulation
Alcohol use
What is metaplasia vs anaplasia vs hyperplasia?
Metaplasia refers to the transformation of one mature cell type into another, essentially changing the type of cell present in a tissue due to stress,
Anaplasia describes a complete loss of cell differentiation, where cells become highly abnormal and poorly differentiated (undifferentiated), often seen in cancerous tissue
Hyperplasia signifies an increase in the number of cells within a tissue, where the cells themselves remain largely normal in appearance, although the overall tissue mass is larger
What is the single best thing to do to prevent infection?
WASH HANDS!
List 5 signs and symptoms of increased ICP.
What labs are drawn for suspected heart attack?
CK
Troponin
What are risk factors for heart disease?
HTN
Diabetes
High cholesterol
Smoking
Sedentary lifestyle
What hormones are associated with stress?
Cortisol, adrenaline (epinephrine)
Incontinence
Loss of feeling
Immobility
Poor blood flow
Skin changes (thinner)
What chemical compounds are released in allergies/inflammation?
Prostaglandins
Histamine
Leukotrienes
Bradykinins
What are s/s of hypovolemia in the body?
Weakness
Fatigue
Dizziness
Dryness
Decr urine
Low BP
Orthostatic hypotention
Inc HR
Altered mental status
Inc sodium
What labs are used to check for systemic inflammation?
CRP
ESR
CBC
1) Vaccines --> HPV
2) Stop smoking
3) Wear sunblock
4) Get screened early if family hx
5) Avoid environmental exposures
What is: a flat, distinct, discolored area of skin that does not change the texture or thickness of the skin
Macule
What are the 3 components of the GCS?
Eyes
Verbal
Motor
What are s/s of hypervolemia in the body?
4+ pulses
Inc BP
Edema
Weight gain
Low sodium
What is the pathophysiology of erythema?
What cells are involved in innate, non-specific immunity?
neutrophils, macrophages, dendritic cells, natural killer (NK) cells, basophils, eosinophils, mast cells, and monocytes
What is a small, solid, raised bump on the skin that is well-defined with distinct borders, usually less than 1 centimeter in size?
Papule
What are s/s of good perfusion?
2+ pulses at normal rate
Good tissue color (pink)
Normal mental status
Cap refill
What are causes of orthostatic hypotension?
Diarrhea
Vomiting
Heart issues
Blood loss
What is atrophy?
What is hypertrophy?
Atrophy is a decrease in muscle mass, while hypertrophy is an increase in muscle mass.
B cells and T cells
What is a small fluid-filled sac on the skin?
Vesicle
What are 3 s/s of a PE?
1) SOB
2) Chest pain
3) Anxiety/nervous/doom
4) Coughing --> maybe blood
5) Dizziness/palpitations
How do lymph nodes affect edema?
Lymph nodes acts as filters in the lymphatic system, and when they are damaged or blocked, they can prevent the proper drainage of fluid, leading to a build-up of fluid in the tissues and causing swelling