History
Pharmacology & Methods
Effects
Complications & Risks
Law & Society
100

What South American empire used coca leaves for stamina and productivity?

What is the Incan Empire?

100

Cocaine’s euphoric effects typically last how long when snorted or injected?

What is 30–90 minutes?

100

Cocaine users often experience what emotional state after the high wears off?

What is depression?

100

Crack lung is a complication of what method of cocaine use?

What is smoking crack?

100

The Fair Sentencing Act of 2010 reduced the crack-to-powder sentencing disparity from what ratio to what ratio?

What is from 100:1 to 18:1?

200

Coca-Cola originally contained how many milligrams of cocaine?

What is 60 mg?

200

What chemical in marijuana mimics endocannabinoids in the brain?

What is THC (delta-9-tetrahydrocannabinol)?

200

Marijuana can cause what mild but common sensory blending effect?

What is synesthesia?

200

Marijuana smokers who smoke one joint a day for 10 years have what percent higher risk of lung cancer compared to nonsmokers?

What is 570% higher risk?

200

Which 2018 law made the Fair Sentencing Act retroactive?

What is the First Step Act?

300

Marijuana was first cultivated in the U.S. in which colony?

What is Jamestown, Virginia?

300

Name two common methods of cocaine use.

What are snorting, injection, smoking, sublingual, or rectal use?

300

What is the name of a cocaine binge followed by a crash?

What is a “coke run”?

300

Cocaine use increases risk of what major cardiovascular events? (Name at least two.)

What are hypertension, coronary artery dissection, cardiac death, or arrhythmias?

300

Marijuana is currently the most widely used illicit drug in which country?

What is the United States?

400

In what decade did cocaine become widely popular in the U.S. again?

What are the 1970s and 1980s?

400

Why do marijuana smokers hold their breath for 20–30 seconds after inhaling?

To maximize THC absorption into the bloodstream.

400

Marijuana intoxication typically occurs in two phases. What are they?

Phase 1: mild anxiety/dry mouth → euphoria/relaxation (2–4 hrs). Phase 2: psychomotor problems, mood swings, depressive symptoms (5–12 hrs).

400

Marijuana abuse has been linked to shrinkage in which two brain structures?

What are the hippocampus and amygdala?

400

In the mid-1980s, cocaine distribution in the U.S. was estimated to be the ___ largest industry.

What is the 7th largest industry?

500

About how many years ago did Chinese physicians begin using cannabis medicinally?

What is nearly 3,000 years ago?

500

Chronic marijuana users may test positive for THC in urine for up to how long?

What is 30 days (with heavy use)?

500

Which drug develops tolerance more rapidly: cocaine or marijuana?

What is cocaine?

500

Cocaine combined with alcohol produces what dangerous chemical?

What is cocaethylene?

500

Why have sentencing disparities between crack and powder cocaine been criticized as unjust?

Because they disproportionately impacted Black communities and contributed to racial bias in drug policy.

M
e
n
u