Medications
In order for a medication to cross into the milk compartment, it must be found here.
What is the mother's blood?
A warm, red, tender spot on the breast that may be palpated as a lump is probably this.
What is a plugged duct?
Even though breastmilk is not a strong source of iron, infants can usually maintain an adequate iron status for 9 months or so because of this.
What is utilization of iron stored in body tissue during gestation?
This characteristic of a drug promotes its transfer into human milk:
a. greater tendency to bind to proteins
b. lesser tendency to dissolve in fats
c. low concentration in maternal plasma
d. lower molecular weight
What is lower molecular weight?
This is a great way to remember that the higher the lipid solubility of a medication, the more likely it will pass into breastmilk.
What is "fat likes fat"? (The high lipid/fat solubility of the medication, the more likely it will pass into the high lipid/fat content of breastmilk.)
Treatment for this type of painful breast issue may include the use of "meaningful" heat and a vasodilator such as nifedipine. It is also characterized by tricolor nipple changes from white to blue to red.
What is vasospasm?
The milk of a mother with a premature infant has ____ protein than the milk of a mother of a full term infant.
What is more?
To minimize the infant dosage of a mother's medication, the med should have a _______ half-life and mom should take it ______ feeding. (2 answers)
What is (1) short and (2) after?
If a medication is highly protein bound, it has a greater or lesser chance of passing into breastmilk?
What is a lesser chance?
This painful issue can occur when skin tissue grows over a nipple opening, blocking the flow of milk from the duct.
What is a milk blister or blocked nipple pore?
Breastmilk is sometimes called "white blood" because of this.
What are anti-infective properties similar to those in blood?
Breastmilk secretion may be inhibited by which of the following: (may be more than one ans.)
a. bromocriptine
b. estrogen
c. fenugreek
d. progesterone
What is bromocriptine, estrogen and progesterone?
If a medication has a large number of daltons (>1,000), will it have less of chance to transfer into human milk, or a greater chance?
What is a lesser chance?
This breast issue may or may not be the result of an unrelieved plugged duct, but it includes the symptoms of a plugged duct, plus flu-like symptoms, and fever/chills. It is often treated with antibiotics.
What is mastitis?
The calcium content of breastmilk is _____ and breastfed infants absorb it at a ________ rate than formula fed infants do. (2 answers)
What is (1) low and (2) higher?
This is the best time to begin an oral contraceptive if a breastfeeding mother has decided to use them.
What is after breastfeeding is well established, preferably at least 6 weeks post-partum?
A relative infant dose (RID) of a medication is considered more favorable if it is < this percentage.
What is 10%?
Anti-fungal medications are often prescribed for a mother and baby suffering from this type of breast infection.
What is candidiasis or yeast infection?
A breastfed infant who has a systemic infection is apt to have a mother whose breastmilk contains a ______ than usual concentration of ______. (2 answers)
What is (1) higher and (2) sIgA?
The following pair of drug properties will encourage a med to pass readily into breastmilk:
a. high lipid solubility/low molecular weight
b. low lipid solubility/low molecular weight
c. not protein bound/high molecular weight
d. protein bound/moderately lipid soluble
What is high lipid solubility and low molecular weight?