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Which volatile anesthetics require adjustments to the vaporizer when administered at high altitudes?
What is Desfluorane-
the desflurane vaporizer is electrically heated to 39 degrees centigrade, which creates a vapor pressure of 2 atmospheres inside the vaporizer, regardless of ambient pressure. The number on the dial reflects the percentage that will be delivered. So at any altitude, when you dial 5%, it will give you 5%. But when that 5% desflurane leaves the vaporizer at high altitude, what is delivered to the patient is 5% of a decreased ambient pressure, so the partial pressure of desflurane in the alveoli will be much less that it would be at sea level. Thus, you will need to dial a higher concentration at high elevation to attain the same clinical effect as at sea level with desflurane (Tec-9) vaporizer