Clinical Manifestations & Pathophysiology
Area of the brain primarily affected by Kuru
What is cerebellum?
Country where Kuru was discovered
What is Papua New Guinea?
Prion disease from the consumption of contaminated beef
What is Cruetzfeldt-Jakob Disease (the variant version)?
Primary clinical manifestation of Kuru: ___ tone
What is muscle?
Meaning of Kuru in the Fore language
What is "to shiver"?
Parkinson's is a __ disease
What is conformational?
Alternative name for Kuru based on behavioral symptoms
What is laughing sickness?
Word for the practice of ritualistic endocannibalism
What is transumption?
Genetically passed down prion disease.
What is Fatal Familial Insomnia or genetic CJD?
Property of the prion protein that allows it to evade defenses and spread throughout the body
What is stability?
What was the primary demographic affected (ex. men, women, adults, children...)
What are women and children?
Disease developed from sporadic CJD
What is Kuru?
Mutated form of normal prion protein PrPC?
What is PrPSc?
The Fore people thought ____ was the cause of Kuru
What is sorcery?
Homozygous amino acid at position 129
What is methionine?