Popular animal due to its small size, calm nature, low cost to house, and ease of genetic manipulation
What is the domestic mouse?
The USDA regulates the use of research animal models under this act.
What is the Animal Welfare Act?
The Animal Welfare Act is designed to regulate the use of only this group of animal models in research, teaching, and testing.
What are warm-blooded vertebrates?
Process which increases, decreases or removes a gene that is already present in the organism.
What is genetic engineering?
Rabbits were used to test this human condition until replaced by a series of chemical reactions.
What is a pregnancy test?
The second most widely used animal research model has many of the attributes of mice, but their larger size and more complex body systems makes them useful for research.
What is the Norway rat?
Some researchers develop their own lines of research animals, often mice and rats through this animal husbandry process.
What is in-house breeding?
This group of animals is regulated only when used for research, not when produced for slaughter or when part of a nutrition, breeding, management, or production efficiency study.
What are livestock (or farm animals)?
These genes are artificially introduced into the genome of another organism.
What are transgenes?
Tissue transplanted from pigs to humans that is one of the most common types of xenotransplantations.
What are heart valves?
The most common fish used as animal models
What are zebrafish?
This class of animal dealer is licensed by the USDA to breed, raise, and sell animals specifically for research, similar to in-house breeders.
What is a Class A dealer?
These two types of rodents make up 95% of all vertebrate animals used in research.
What are laboratory rats and mice?
Group of animal species includes macaques, monkeys, marmosets, baboons, and chimpanzees that account for less than 0.5% of all animals used in current medical research.
What are non-human primates (NHP)?
This latin phrase refers to the testing in the body of a living animal.
What is "in vivo"?
This fly and this little known multi-celled "worm" are the two most common insects (yes, insects) used as animal models.
What are the fruit fly and nematode?
This class of animal dealer licensed by the USDA does not raise their own animals, but acquires them from many different sources.
What is a Class B dealer?
These two species of rodents were among the first animals used in medical research.
What are guinea pigs and rabbits?
Named because of genetic engineering techniques that involve inserting non-mice genes into the mouse genome while deleting others.
What are "knock out" mice?
Researchers have used this eye irritancy tests on rabbits since the 1940's.
What is the Draize test?
The most common single-celled organism used as animal models.
What is saccharomycetales yeast?
Registered research institutions must submit an annual report to this agency regarding their use of animal models.
What is the Animal and Plant Health Inspection Service (APHIS)?
In recent decades, the use of these two domestic animals has decreased due to public pressure.
What are dogs and cats?
The process of grafting or transplanting organs and tissues between members of different animal species.
What is xenotransplantation?
Use of non-human primates is critical to understanding how to prevent and treat these three infectious diseases.
What is Zika, Covid, and Ebola?