Unit 01
What types of costs are associated with a specific research project?
Direct
Fixed
Variable
Indirect
Direct
If a barrier facility is designated for bioexclusion, what is it designed to do?
To prevent microorganisms from entering an area
To keep animals inside an area
To keep pathogens inside an area
To prevent personnel who are not wearing PPE from entering an area
To prevent microorganisms from entering an area
What division of the nervous system is made up of the spinal cord and the brain?
Peripheral
Central
Autonomic
Cranial
Central
What is the general guideline for selecting the size of syringe to use?
Use a syringe that is about twice the size of the fluid volume that will be injected or collected
Use a syringe the same size as the amount of fluid to inject or collect
Use the largest syringe available to ensure adequate space for the fluid
Size of the syringe is not a factor
Use a syringe that is about twice the size of the fluid volume that will be injected or collected.
What is bloat?
Difficulty maintaining balance after eating due to overeating
High blood pressure
A large amount of blood in the urine
An abnormal amount of air, food, or liquid in the stomach
An abnormal amount of air, food, or liquid in the stomach
How long does the United States Department of Agriculture (USDA) require that protocol records be retained?
3 years
1 year
5 years
6 months
3 years
What is another name for a sporicide?
Sanitizer
Disinfectant
Cleaner
Sterilizer
Sterilizer
In which structure do sperm mature and are also stored?
Epididymis
Ductus deferens
Seminal vesicles
Prostate
Epididymis
If instruments have been sterilized with aldehydes, what must be done before using them?
They must be rinsed with sterile saline
They must be placed in alcohol
They must be cooled
They must be exposed to air
They must be rinsed with sterile saline
What occurs when the immune system over-responds and causes disease itself?
Allergy
Inflammation
Immunity
Septicemia
Allergy
How often must the controlled substances inventory list be updated?
Every 2 years
Every 5 years
Every 3 years
Every year
Every 2 years
What is the type of filter that removes large, solid waste?
Chemical
Activated carbon
Mechanical
Biologic
Mechanical
What is a key difference between permanent cartilage and bone?
Bones do not have a matrix
Permanent cartilage is not calcified
Permanent cartilage is composed of bone cells
All of the above
Permanent cartilage is not calcified
How do the drugs used in chemically-induced immunodeficiency work?
They interrupt DNA or RNA synthesis
They use radiation to damage cells
They attack B cells
They turn genes off
They interrupt DNA or RNA synthesis
Which type of disease is characterized by a sudden outbreak affecting a large number of animals?
Enzootic
Endemic
Epidemic
Epizootic
Epizootic
Who can restrict or withdraw approval of the Animal Welfare Assurance if an institution fails at its responsibilities?
Institutional Animal Care and Use Committee (IACUC)
Food and Drug Administration (FDA)
Office of Laboratory Animal Welfare (OLAW)
United States Department of Agriculture (USDA)
Office of Laboratory Animal Welfare (OLAW)
What is considered an acceptable general standard for room air changes per hour in animal rooms?
10-15
15-20
5-10
1-5
10-15
What do the hormones produced in the anterior pituitary gland regulate?
Growth, metabolism, and other endocrine glands
Metabolic rate
Blood calcium concentration
The autonomic nervous system
Growth, metabolism, and other endocrine glands
Which type of suture material is more pliable and makes knot tying easier?
Multifilament
Absorbable
Synthetic
Monofilament
Multifilament
What is TRUE about bloat in frogs?
It is caused by a virus
It is a congenital disease
It results from poor diet
It may impair equilibrium in the water
It may impair equilibrium in the water
Which of the following requires that protocols for United States Department of Agriculture (USDA)-covered species may only be approved for 1 year?
Animal Welfare Regulations (AWR)
Public Health Service (PHS) Policy
Guide for the Care and Use of Laboratory Animals (the Guide)
Good Laboratory Practice Regulations
Animal Welfare Regulations (AWR)
During the time when the biologic filter is being established, what can increase and remain high?
Chlorine and nitrite levels
Nitrite and ammonia levels
Ammonia and chlorine levels
Sodium and calcium levels
Nitrite and ammonia levels
What is an animal called that has some cells containing the new gene and some without the new gene?
Wild type
Knockout
Chimera
Null
Chimera
What type of study investigates reproductive toxicity in male and female animals?
Segment III
Segment I
Segment II
Segment IV
Segment I
What occurs when an animal goes into shock?
The body temperature increases
Nerve signals cannot respond
A blood clot lodges in the brain
The peripheral circulation fails
The peripheral circulation fails