Chemistry
Molecular Biology
Immunology
Genetic Engineering
Gnotobiotics
100
The term used to describe the bonding capacity of an atom
What is valence
100
_____ is using specialized DNA technology to produce multiple, exact copies of a single gene
What is cloning
100
This type of immunity results in only temporary resistance, received across the placenta or via antiserum injections.
What is passive immunity
100
These mice induce pseudopregnancy in females
What are vasectomized males
100
This type of gnotobiote animals have normal flora but are free from particular organisms
What is SPF (specific pathogen free)
200
_____ contain long chains of hydrocarbons attached to one another
What are lipids
200
The product of an egg and sperm cell uniting, containing paired chromosomes (one set from mother, one set from father)
What is a zygote
200
These cells provide antibody-mediated immunity and develop into plasma cells to destroy antigens
What are B lymphocytes (B cells)
200
This is an environmental factor that can negatively impact mating, ovulation, birthing, eating, and other mouse behaviors.
What is lighting (noise, vibrations, and pheromones can also impact normal activity)
200
This type of cabinet provides a large volume of linear-flowing, filtered, sterile air. Removes airborne microorganisms from cage environment.
What is laminar flow cabinet or laminar flow racks
300
Maltose, sucrose, and lactose are examples of ______
What are disaccharides
300
When DNA fragments are produced by an investigator, this test is used to determine if the desired fragment is present
What is Southern blot
300
This immunoglobulin is the first to be detected in response to an initial exposure to an antigen
What is IgM
300
Egg donor females need to receive an IP injection of _____ to cause superovulating.
What is PMSG (pregnant mare serum gonadotropin) and hCG (human chorionic gonadotropin)
300
Survival of pups drops dramatically if the hysterectomy is performed more than ___ hours before normal birth
What is 12
400
Many of these make up nucleic acids and each one has 3 components (a nitrogenous base, a pentose sugar, & a phosphate group)
What is a nucleotide
400
This is the cellular process where the mRNA is read and used to synthesize proteins. Occurs in the cytoplasm.
What is translation
400
These are used to boost the effectiveness of inactivated/killed vaccines
What are adjuvants
400
The percentage of the genes in the genome of a mouse that can be directly aligned with the same gene in the genome of humans
What is 40%
400
This is a solution containing a variety of normal intestinal flora, used by many commercial vendors of rodents
What is Schaedler cocktail
500
____ constitute half of the body's dry weight, perform the widest range of functions, and grouped according to their role
What are proteins
500
During translation, this cell component "reads" the "code" contained in the mRNA, where protein synthesis takes place
What is the ribosome
500
This is an immunosuppressant drug that specifically inhibits T cell activation (given to people that have had a tissue transplant)
What is Cyclosporin A
500
The kind of cells used to produce transgenic mice by gene-targeted mutations
What are embryonic stem cells
500
Which anatomical feature is enlarged in axenic animals?
What is cecum
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