Endocrine System Basics
Hormone Mechanisms
Hormone Release Stimuli
Hypothalamus & Pituitary
Endocrine Regulation & Homeostasis
100

This major control system works with the nervous system but acts slower and lasts longer.

What is the endocrine system

100

Water-soluble hormones bind to receptors located here.

What is the plasma membrane

100

Low Ca²⁺ levels stimulate this hormone through humoral control.

What is parathyroid hormone (PTH)

100

This structure connects the hypothalamus to the pituitary gland.

What is the infundibulum?


100

Cells respond to a hormone ONLY if they contain these.

What are specific receptors?


200

Endocrine glands release hormones into this, allowing long-distance signalling.

What is the bloodstream / lymph?


200

cAMP is turned off by this enzyme.

What is phosphodiesterase

200

Sympathetic nerves stimulating the adrenal medulla is an example of this type of endocrine stimulus.

What is neural stimulation

200

The anterior pituitary is controlled by hormones delivered through this unique vascular system.

What is the hypophyseal portal system?


200

Persistently high hormone levels lead to this decrease in receptor number.

What is down-regulation

300

These glands have both endocrine AND exocrine functions.

What are the pancreas, gonads, and placenta

300

Steroid hormones act by initiating this nuclear process.

What is gene transcription?


300

The hypothalamus releasing TRH to control TSH is an example of this stimulus type.

What is hormonal stimulation

300

This hypothalamic hormone inhibits prolactin release.

What is PIH (dopamine)?


300

Steroid hormones have long half-lives because they circulate this way.

What is bound to plasma proteins?


400

Steroid hormones are synthesized from this molecule.

What is cholesterol

400

This intracellular transcription factor is activated by cAMP signalling.

What is CREB?


400

Under severe stress, this system overrides insulin release to increase blood glucose.

What are the hypothalamus and sympathetic nervous system

400

Oxytocin and ADH are synthesized here before being stored in the posterior pituitary.

What are the PVN (oxytocin) and SON (ADH) nuclei?


400

T3/T4 inhibiting release of TRH and TSH is an example of this homeostatic mechanism.

What is negative feedback

500

This endocrine organ is considered neuroendocrine because it links neural activity to hormonal output.

What is the hypothalamus?

500

Steroid hormone responses take longer because proteins must be made through these two processes.

What are transcription and translation?

500

High K⁺ directly stimulates the adrenal cortex to release this hormone.

What is aldosterone

500

ACTH, TSH, FSH, and LH are all considered this type of hormone because they control other glands.

What are tropic (tropin) hormones

500

This determines how strongly a receptor binds to its hormone.

What is receptor affinity

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