General
This is a term used to describe a group of malignant disorder affecting the blood and blood forming tissues of the bone marrow, lymph system, and spleen
What is Leukemia
Name the four major types of leukemia
What is Acute Lymphocytic leukemia (ALL), Acute myelogenous leukemia (AML), chronic myelogenous leukemia (CML) and chronic lymphocytic leukemia (CLL)
Auer rods are present in this type of leukemia
What is AML?
Primary methods of diagnosing and classifying the subtypes of leukemia
What is peripheral blood evaluation and bone marrow examination?
The mainstay treatment for leukemia that involves cellular kinetics, use of multiple drug
What is Cytotoxic Chemotherapy?
Sudden onset of high fever, Thrombocytopenia, Weakness, and recurrent Infections deal with this type of Leukemia?
What is Acute Myelogenous Leukemia?
Its onset is often abrupt and dramatic, cause serious infection and bleeding, characterized by uncontrolled proliferation of myeloblasts, and causes bone marrow hyperplasia
What is AML?
Unique subtype of acute myeloid leukemia
What is acute promyelocytic leukemia?
Presence of smudge cells on peripheral blood smear with this type of leukemia
What is CLL?
Possible type of complication of chemotherapy seen in acute leukemia
What is tumor lysis syndrome?
type of WBC affected: lymphocytes
what is lymphocytic leukemia?
Most common type of leukemia in children, immature lymphocytes proliferate the bone marrow
What is ALL?
Associated with translocation t(15,17)
What is subtype of AML, APL?
Lab abnormalities seen in leukemias
What is Anemia, thrombocytopenia, leukocytosis?
Treatment in those with APL subtype AML
What is All-trans-retinoic acid?
type of WBC affected: granulocytes or monocytes
What is myelogenous leukemia?
Least aggressive type of leukemia
What is CML?
Treatment for AML
What is all-trans retinoic acid?
Findings on imaging
What is hepatomegaly, splenomegaly, lymphadenopathy?
Treatment of CML
What is tyrosine kinase inhibitor, Imatinib?
frequently has no symptoms, may have fever, night sweat, weight loss fatigue and frequent infections
What is CLL?
Associated with translocation t(9,22). (The fusion of the BCR gene on chromosome 22 with the ABL1 gene on chromosome 9)
What is CML?