General
Congenital
Acquired
Final Jeopardy
100
Other than localized and HIV-associated the most common type.
What is acquired partial?
100
Common compensatory metabolic abnormality associated with most lipodystrophies.
What is insulin resistance or diabetes mellitus?
100
Common compensatory organ hypertrophy in lipodystrophies.
What is hepatomegaly?
100
Eponyms associated with congenital generalized, congenital partial, acquired generalized, and acquired partial lipodystrophy. And, which picture goes with which type of partial lipodystrophy.
What are Berardinelli-Seip (CG), Kobberling-Dunnigan (CP), Lawrence-Seip (AG), and Barraquer-Simons (AP)?
200
1 of 2 characteristic compensatory fat deposits in patients with HIV-associated lipodystrophy.
What is buffalo hump or protease pouch?
200
Other than GLUT4 and caveolin, more common genes associated with congenital generalized lipodystrophy.
What are AGPAT2 (BSCL1) and Seipin (BSCL2)?
200
Other than idiopathic, the 2 major types of acquired generalized lipodystrophy.
What are post-panniculitis and autoimmune-related?
300
Trade name and/or chemical compound FDA-approved for treating HIV-associated lipodystrophy.
What Sculptra (poly-L-lactic acid)? Radiesse (calcium hydroxyapatite) also sometimes used.
300
Genes associated with congenital partial lipodystrophy.
What are PPARgamma and LMNA?
300
One of the 2 most common types of autoimmune diseases associated with acquired generalize lipodystrophy.
What is DM or JRA?
400
Localized lipoatrophy most associated with women administrative assistants.
What is lipoatrophia semicircularis?
400
Mutations of this gene is associated with Werner's syndrome, which is considered the adult form of Progeria, which also results from LMNA mutation.
What is RECQL2?
400
Specific complement deficiency associated with aquired partial lipodystrophy.
What is C3? Note that C3 nephritic factor is elevated in these patients.
500
Specific protease inhibitor associated with HIV-associated lipodystrophy and one of its other cutaneous side affect.
What are indinavir and alopecia or paronychia?
500
Gene mutation associated with leprechaunism, and any 3 major features of AREDYLD syndrome.
What are insulin receptor and AcroRenal Ectodermal Dysplasia Lipoatrophic Diabetes?
500
Most common viral illness associated with acquired partial lipodystrophy.
What is measles (RNA paramyxovirus)?
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